Harold S. Javitz

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This study evaluated association between common and rare sequence variants in 10 nicotinic acetylcholine receptor subunit genes and the severity of nausea 21 days after initiating the standard, Food and Drug Administration-approved varenicline regimen for smoking cessation. A total of 397 participants from a randomized clinical effectiveness trial with(More)
This report describes the design and implementation of a real-time intrusion-detection expert system (IDES) designed and developed by SRI International. IDES is an independent system that monitors the activities of different types of subjects, such as users and remote hosts, of a target system to detect security violations by both insiders and outsiders as(More)
BACKGROUND Retrospectively collected data about the development and maintenance of behaviors that impact health are a valuable source of information. Establishing the reliability of retrospective measures is a necessary step in determining the utility of that methodology and in studying behaviors in the context of risk and protective factors. OBJECTIVE(More)
The association between depression and self-focused language has been found to varying extents across studies. The presence or absence of the association may depend on the communicative context. Based on Beck's depression model, a broad, evaluative self-focused question was predicted more likely to elicit a stronger association than a full interview(More)
This project studied the convergent validity of current recall of tobacco-related health behaviors, compared with prospective self-report collected earlier at two sites. Cohorts were from the Oregon Research Institute at Eugene (N = 346, collected 19.5 years earlier) and the University of Pittsburgh, Pennsylvania (N = 294, collected 3.9 years earlier).(More)
The present study correlates empirically constructed prospective adolescent smoking trajectories with indicators of nicotine dependence assessed in adolescence and in adulthood. Excluding individuals who reported no smoking during repeat assessment (nonadopters), we identified five smoking trajectory groups: experimenters (n=116, 48.5%), late increasers(More)
INTRODUCTION Metabolic enzyme variation and other patient and environmental characteristics influence smoking behaviors, treatment success, and risk of related disease. Population-specific variation in metabolic genes contributes to challenges in developing and optimizing pharmacogenetic interventions. We applied a custom genome-wide genotyping array for(More)