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  • Donald R. Senger, Stephen J. Galli, Ann M. Dvorak, Carole A. Perruzzi, V. Susan Harvey, Harold F. Dvorak
  • Biology, Medicine
  • Science
  • 1983 (First Publication: 25 February 1983)
  • Tumor ascites fluids from guinea pigs, hamsters, and mice contain activity that rapidly increases microvascular permeability. Similar activity is also secreted by these tumor cells and a variety ofExpand
  • Harold F. Dvorak, Lawrence F. Brown, Michael Detmar, Ann M. Dvorak
  • Biology, Medicine
  • The American journal of pathology
  • 1995 (First Publication: 1 May 1995)
  • VPF/VEGF is a multifunctional cytokine that contributes to angiogenesis by both direct and indirect mechanisms. On the one hand, VPF/VEGF stimulates the ECs lining nearby microvessels to proliferate,Expand
  • Harold F. Dvorak
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2002 (First Publication: 1 November 2002)
  • Vascular endothelial growth factor A (VEGF-A), the founding member of the vascular permeability factor (VPF)/VEGF family of proteins, is an important angiogenic cytokine with critical roles in tumorExpand
  • Lawrence F. Brown, K. T. Yeo, +4 authors Livingston Van de Water
  • Medicine
  • The Journal of experimental medicine
  • 1992 (First Publication: 1 November 1992)
  • Persistent microvascular hyperpermeability to plasma proteins even after the cessation of injury is a characteristic but poorly understood feature of normal wound healing. It results in extravasationExpand
  • Harold F. Dvorak, Janice A. Nagy, Dian Feng, Lawrence F. Brown, Ann M. Dvorak
  • Medicine, Biology
  • Current topics in microbiology and immunology
  • 1999
  • This Chapter has reviewed the literature concerning VPF/VEGF as a potent vascular permeabilizing cytokine. In accord with this important role, microvessels have been found to be hyperpermeable toExpand