Harold B Haley

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Sarcoidosis is a chronic granulomatous disease of unknown aetiology in which the primary cytokine tumour necrosis factor (TNF)-alpha appears to play a major role. Older immune-modulating drugs including corticosteroids, antimalarials and thalidomide, as well as cytotoxic drugs with immune modulatory effects, have been used to control disease. We present a(More)
The level of protein-bound hexoses was compared in several fractions of electro-phoretically separated globulins in the sera of normal and wounded rats. Changes in the concentration of protein components which were not apparent from the amount of total protein of different fractions could be identified. Although wounding resulted in no change from the(More)
To characterize infections and their management in oncology patients at the end of life, we conducted a review of the literature. Eight studies assessing infection in 957 patients with various malignancies were identified. Forty-two percent of terminally ill patients developed infections in the final phase of care. The greatest frequency of treatment with(More)
The effect of wounding on the uptake of Ssoo labeled amino acids by leucocytes of the blood was studied. Although a significant increase in the rate of uptake of cystine was observed after wounding, there appeared to be no effect on the incorporation of methionine. The effect was most pronounced on the third day after wounding; by the seventh day, the(More)