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  • Sara L Sawyer, Lily I. Wu, Michael Emerman, Harmit Singh Malik
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Publication: 22 February 2005)
  • Primate genomes encode a variety of innate immune strategies to defend themselves against retroviruses. One of these, TRIM5alpha, can restrict diverse retroviruses in a species-specific manner. Thus,Expand
  • Efrem S Lim, Oliver I Fregoso, Connor McCoy, Frederick A Matsen, Harmit Singh Malik, Michael Emerman
  • Medicine, Biology
  • Cell host & microbe
  • 2012 (First Publication: 16 February 2012)
  • The human SAMHD1 protein potently restricts lentiviral infection in dendritic cells and monocyte/macrophages but is antagonized by the primate lentiviral protein Vpx, which targets SAMHD1 forExpand