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Mild cognitive impairment has frequently been reported for patients in the early stages of multiple sclerosis. The aim of the present study was to measure whether altered cortical activation during a sustained attention task occurs along with limited extent of neuropsychological problems. Expanded brain activation of multiple sclerosis patients with normal(More)
In vivo proton magnetic resonance spectroscopy (1H-MRS) has been used to assess biochemical changes that occur in demyelinating lesions and in normal appearing white matter (NAWM) in multiple sclerosis (MS) patients. N-acetylaspartate (NAA) levels in MS patients may indicate neural viability. In early stages of MS, patients may suffer from slight cognitive(More)
PURPOSE Comparative evaluation of regional brain perfusion measured by HMPAO-SPECT of patients with mild cognitive impairment (MCI), dementia of Alzheimer's type (DAT) and depression with cognitive impairment (DCI). METHODS A total of 736 patients were investigated because of suspected cognitive dysfunction. After exclusion of patients with other forms of(More)
Humans represent numbers along a left-to-right oriented Mental Number Line (MNL). Neglect patients seem to neglect the left part of the MNL, namely the smaller numbers within a given numerical interval. However, until now all studies examining numerical representation have focussed on single-digit numbers or two-digit numbers smaller than 50. In this study,(More)
RPL (pronounced " ripple ") is the most expressive path language for navigating in RDF graphs proposed to date that can still be evaluated with polynomial combined complexity. RPL is a lean language well-suited for integration into RDF rule languages. This integration enables a limited form of recursion for traversing RDF paths of unknown length at almost(More)
Recent evidence suggests that neglect patients seem to have particular problems representing relatively smaller numbers corresponding to the left part of the mental number line. However, while this indicates space-based neglect for representational number space little is known about whether and - if so - how object-based neglect influences number(More)
Salzburg. Member of the method unit " Neuroimaging and brain stimulation " (Dr. Martin Kronbichler), member of the research cluster " Language, reading, and dyslexia " (Prof. Florian Hutzler), and associated faculty member of the doctoral college " Imaging the mind " (Prof. PhD student in the FWF-(Austrian Science Fund) (project: "Brain dysfunctions(More)
Due to the increasing importance of early recognition and differential diagnosis of dementias, cerebral perfusion scans using "single photon emission computed tomography" (SPECT) are increasingly integrated into the examination routine. The goal of this study was to check the diagnostic validity of SPECT scans of MCI- and DAT-patients, two subgroups out of(More)
There is some evidence for a relation between critical life-events and the excessive drinking of alcoholics; the present study fits well into the approach of life-event-research assuming an aggregation of life-events and difficulties to elicit or cause excessive drinking. In all 25 men who were in danger of becoming excessive drinkers and 29 who were(More)
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