- Full text PDF available (3)
Taxanes (T) plus bevacizumab (B) and taxanes plus capecitabine (X) showed better progression-free survival (PFS) compared to taxanes alone. Since life-threatening or highly symptomatic situations require polychemotherapy in metastatic breast cancer (MBC), combination of taxanes, capecitabine plus bevacizumab appears reasonable. TABEA (NCT01200212), a… (More)
Over the last few years our group has been strongly involved in the study of the chemistry of oligosilanes. 1,2 In particular, the development of a convenient synthetic access to structurally diverse oligosilanyl anions 3À6 allowed the preparation of a huge variety of previously unknown small polysilanes. Some 40 years ago Ishikawa and Kumada discovered the… (More)
Lewis acid-catalyzed rearrangement reactions of trimethylgermylated small permethylated oligosilanes were found to show a strong tendency of the germanium atoms to move to the more highly silylated positions of the molecule. This makes possible the construction of molecules with high germanium content in the core parts of the molecules by the following… (More)
b S Supporting Information ' INTRODUCTION In recent years small alkylated polysilanes 1 have been used to investigate the conformational dependency of the σ-bond electron delocalization of these compounds. 2À8 Some reports have dealt with branched derivatives of this substance class, which were either den-drimers 9À14 or linear silanes with branched end… (More)
Reactions of potassium oligosilanyls with ZnCl(2) lead to the formation of oligosilanylzinc compounds with zinc's coordination sphere expanded by ligation of TMEDA, an additional oligosilanyl group, or a chloride ion.
Salt elimination reactions of tris(trimethylsilyl)silyl potassium (1), and two 1,4-dipotassiooligosilanes (3, 5) with 2,2,6,6-tetramethylpiperidinodichloroborane and diethylaminodichlorophosphane have generated open (2), cyclic (4) and bicyclic (6) bora- and phosphaoligosilanes. A monosilylated phosphane and the two five-membered cyclosilanes have been… (More)