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In vivo and in vitro Cellular Ingrowthinto a New Generation of Artificial Ligaments
Artificial ligaments are a useful tool in ligament reconstruction. Although the new generation of artificial ligaments shows encouraging clinical results, in contrast to earlier generations studiesExpand
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Heat shock protein expression in the transplanted human kidney
Abstract. Heat shock proteins (HSPs) have been shown to represent potential target molecules for T-cell-mediated allograft rejection in heart and kidney transplants. In the present study, weExpand
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Suramin suppresses growth, alkaline-phosphatase and telomerase activity of human osteosarcoma cells in vitro.
Neoadjuvant chemotherapy in osteosarcoma improves the survival dramatically, but there is currents drug resistance in about 25% of patients, leading researchers to investigate alternative therapyExpand
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Serum levels of TNF-beta and sTNF-R in patients with malignant bone tumours.
OBJECTIVE To determine serum levels of TNF-beta and soluble TNF-R in patients with primary highly malignant bone tumours. PATIENTS AND METHODS Sera of 27 patients with highly malignant osteosarcomaExpand
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Hyperthermia increases the susceptibility of chondro- and osteosarcoma cells to natural killer cell-mediated lysis.
As an adjuvant to chemotherapy hyperthermia has proven to be successful as a treatment for osteo- and chondrosarcoma patients. The aim of this study was to investigate whether hyperthermia couldExpand
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Effects of hyperthermia on heat shock protein expression, alkaline phosphatase activity and proliferation in human osteosarcoma cells
Hyperthermia can be used as a possible adjuvant therapy in treatment of cancer patients. In this study, the direct effect of hyperthermia on osteosarcoma derived cell lines HOS85, MG‐63 and SaOS‐2Expand
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Heat shock protein 72 expression in chondrosarcoma correlates with differentiation
Purpose: Heat shock proteins (hsp) are involved in tumor immunity, and a correlation with survival, occurrence of metastases, and drug resistance has been reported. It was the aim of this study toExpand
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Serum concentrations of sCD30 and sCD40L in patients with malignant bone tumours
SummaryThe aim of this study was to evaluate serum levels of both soluble CD30 (sCD30) and soluble CD40 ligand (sCD40L) in patients with malignant bone tumours and to determine their ability to serveExpand
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Serum concentrations of APO-1/Fas and interleukin-1beta-converting enzyme in osteosarcoma correlate with response to chemotherapy.
BACKGROUND Cytotoxic drugs used in neoadjuvant chemotherapy may exert their effect by activation of apoptosis. Both APO-1/Fas and Interleukin-1beta-converting (ICE)/caspase-1 are believed to act asExpand
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Heat shock protein expression in the transplanted human kidney
Abstract Heat shock proteins (HSPs) have been shown to represent potential target molecules for T‐cell‐mediated allograft rejection in heart and kidney transplants. In the present study, we thereforeExpand