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In vivo and in vitro Cellular Ingrowthinto a New Generation of Artificial Ligaments
TLDR
For the first time the cellular ingrowth into the LARS ligament is demonstrated, which might explain the strength and the inert behavior of the ligament without the synovialitis shown in clinical studies.
Heat shock protein expression in the transplanted human kidney
TLDR
Rejection episodes are paralleled by an increased but differential expression of HSPs in the glomerular, tubular, and vascular compartments of the kidney, which might explain the presence of H SP-reactive T lymphocytes in rejected allografts.
Serum levels of TNF-beta and sTNF-R in patients with malignant bone tumours.
TLDR
In patients with high-grade osteosarcoma TNF-beta levels seem to be of predictive value and both TNF -beta and sTNF-R seem to been of diagnostic value for differentiation between high- grade osteosARcoma and Ewing sarcoma.
Hyperthermia increases the susceptibility of chondro- and osteosarcoma cells to natural killer cell-mediated lysis.
TLDR
Hyperthermia increases HSP72 expression in osteo- and chondrosarcoma cells and their susceptibility to NK-cell-mediated lysis, which may lead to new therapeutic strategies, using hyperthermia to improve immunological defense against chondro- and osteosarcomA cells.
Effects of hyperthermia on heat shock protein expression, alkaline phosphatase activity and proliferation in human osteosarcoma cells
TLDR
The data suggest that hyperthermia has an anti‐tumour effect on cancers of the bone and might, therefore, become an adjuvant treatment option in treatment of cancer patients.
Heat shock protein 72 expression in chondrosarcoma correlates with differentiation
TLDR
This study shows a different expression of hsps in chondrosarcomas and chondromas, together with the correlation of hsp72 expression with low differentiation, which could lead to new experimental and diagnostic strategies.
Serum concentrations of sCD30 and sCD40L in patients with malignant bone tumours
TLDR
Serum levels of both soluble CD30 and soluble CD40 ligand in patients with malignant bone tumours were evaluated to determine their ability to serve as serum markers and seem to be of diagnostic value in osteosarcoma and Ewing sarcoma.
Serum concentrations of APO-1/Fas and interleukin-1beta-converting enzyme in osteosarcoma correlate with response to chemotherapy.
TLDR
Elevated serum levels of both APO-1 and ICE seem to be predictive of good response to chemotherapy in highly-malignant osteosarcoma.
Heat shock protein expression in the transplanted human kidney
TLDR
Rejection episodes are paralleled by an increased but differential expression of HSPs in the glomerular, tubular, and vascular compartments of the kidney, which might explain the presence of H SP‐reactive T lymphocytes in rejected allografts.