Haoxin Li

1Michael A Skinnider
1Andrew L H Webster
1Duncan Webster
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Microbial natural products are an invaluable source of evolved bioactive small molecules and pharmaceutical agents. Next-generation and metagenomic sequencing indicates untapped genomic potential, yet high rediscovery rates of known metabolites increasingly frustrate conventional natural product screening programs. New methods to connect biosynthetic gene(More)
The treatment of microbial infections is becoming increasingly challenging because of limited therapeutic options and the growing number of pathogenic strains that are resistant to current antibiotics. There is an urgent need to identify molecules with novel modes of action to facilitate the development of new and more effective therapeutic agents. The(More)
The risk analysis of an irrigation water allocation strategy based on physical mechanisms is critically important in practice. Conventional risk analysis only considers the role of the channel system and ignores the factors related to on-farm ponds. This paper proposes a channel-pond joint water supply mode (CPJM) based on copula approaches. Two copulas,(More)
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