Hao-xiang Xu

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OBJECTIVE To investigate the changes in cell proliferation and retinoic acid receptor gamma (RARgamma) mRNA expression in normal human keratinocytes after acitretin treatment and/or narrow-band ultraviolet-B irradiation. METHODS Normal human keratinocytes were exposed to irradiation with 100 mJ/cm square NB-UVB and/or subsequent 12-hour incubation with(More)
In this study, we investigated the members of a four-generation family from Jiangsu province of China with typical dyschromatosis symmetrica hereditaria [Figure 1a]. The proband of this family is a 60-year-old male with a history, from 6 to 7 months age, of hyperpigmented and hypopigmented macules on the distal extremities [Figure 1b and c]. The typical(More)
OBJECTIVE To evaluate the effect of neuronal differentiation induced by nerve growth factor (NGF) on the tolerance-dosage of ultraviolet radiation of PC12 Cells. METHODS Neuron-differentiated PC12 cells and untreated PC12 cells were exposed to different ultraviolet radiation dosage of 10, 30, 60, 80, 100, and 200 mJ/cm2. Cell survival rates were(More)
BACKGROUND Receptor interacting protein 1 (RIP1), which plays a key role in apoptosis, cell survival and programmed cell necrosis, is one of the most important proteins in the RIP family. The purpose of this study was to investigate the roles of RIP1 in the apoptosis, the generation of reactive oxygen species (ROS) and the expression of matrix(More)
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