Hao-hao Chen

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Rag1 plays a critical role in the development and maturation of lymphocytes, and is related to immune memory functions. Deletion of Rag1 results in a lack of mature functional B and T lymphocytes. Rag1 transcription is most apparent in regions of the postnatal brain with high neuronal cell density--the cerebellum and the hippocampal formation, both of which(More)
In September 2014, severe stem blight, foot rot and storage tuber rot on sweet potato were observed in experimental fields in Sanmen County, Zhejiang Province, China. The causal agent was identified as Plenodomus destruens on the basis of morphological characteristics and molecular identification. In pathogenicity tests, P. destruens caused severe wilting,(More)
Post-stroke depression is associated with reduced expression of brain-derived neurotrophic factor (BDNF). In this study, we evaluated whether BDNF overexpression affects depression-like behavior in a rat model of post-stroke depression. The middle cerebral artery was occluded to produce a model of focal cerebral ischemia. These rats were then subjected to(More)
Because there is no curative treatment for spinal cord injury, establishing an ideal animal model is important to identify injury mechanisms and develop therapies for individuals suffering from spinal cord injuries. In this article, we systematically review and analyze various kinds of animal models of spinal cord injury and assess their advantages and(More)
OBJECTIVE To investigate the effects of formaldehyde inhalation on the morphological damage, and Glu, GABA and NOS contents in olfactory bulb and hippocampus of rats. METHODS Twenty SD rats were equally divided into two groups: rats in the control group inhaled fresh air, while the animals in experimental group were exposed to the air containing(More)
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