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Dynamic properties of Legionella‐containing phagosomes in Dictyostelium amoebae
The natural hosts of the bacterial pathogen Legionella pneumophila are amoebae and protozoa. In these hosts, as in human macrophages, the pathogen enters the cell through phagocytosis, then rapidly… Expand
GRIM-19, a Cell Death Regulatory Protein, Is Essential for Assembly and Function of Mitochondrial Complex I
- Guochang Huang, Hao Lu, +6 authors X. Cao
- Medicine, Biology
- Molecular and Cellular Biology
- 1 October 2004
ABSTRACT Mitochondria play essential roles in cellular energy production via the oxidative phosphorylation system (OXPHOS) consisting of five multiprotein complexes and also in the initiation of… Expand
GRIM-19 is essential for maintenance of mitochondrial membrane potential.
GRIM-19 was found to copurify with complex I of mitochondrial respiratory chain and subsequently was demonstrated to be involved in complex I assembly and activity. To further understand its function… Expand
Use of 13C labeling to assess carbon partitioning in transgenic and nontransgenic (parental) rice and their rhizosphere soil microbial communities.
- W. Wu, W. Liu, Hao Lu, Y. Chen, Devare Medha, Thies Janice
- Biology, Medicine
- FEMS microbiology ecology
Photosynthetic assimilation of CO2 is a primary source of carbon in soil and root exudates and can influence the community dynamics of rhizosphere organisms. Thus, if carbon partitioning is affected… Expand
Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum
The Gram‐negative bacterium Legionella pneumophila is a facultative intracellular pathogen of free‐living amoebae and mammalian phagocytes. L. pneumophila is engulfed in phagosomes that initially… Expand
Transgenic Bt rice does not affect enzyme activities and microbial composition in the rhizosphere during crop development
Use of transgenic crops, including those expressing the insecticidal Cry protein from Bt, is increasing at a rapid rate in worldwide. Field and laboratory studies of transgenic Bt crops have been… Expand
An octamer of enolase from Streptococcus suis
Enolase is a conserved cytoplasmic metalloenzyme existing universally in both eukaryotic and prokaryotic cells. The enzyme can also locate on the cell surface and bind to plasminogen, via which… Expand
Cyanidin-3-O-galactoside and blueberry extracts supplementation improves spatial memory and regulates hippocampal ERK expression in senescence-accelerated mice.
- Long Tan, Hong Peng Yang, +6 authors Y. Jiang
- Biomedical and environmental sciences : BES
OBJECTIVE To investigate whether the antioxidation and the regulation on the Extracellular Regulated Protein Kinases (ERK) signaling pathway are involved in the protective effects of blueberry on… Expand
Genomic and antigenic characterization of the newly emerging Chinese duck egg-drop syndrome flavivirus: genomic comparison with Tembusu and Sitiawan viruses.
- Peipei Liu, Hao Lu, +10 authors G. Gao
- Biology, Medicine
- The Journal of general virology
- 1 October 2012
Duck egg-drop syndrome virus (DEDSV) is a newly emerging pathogenic flavivirus causing avian diseases in China. The infection occurs in laying ducks characterized by a severe drop in egg production… Expand
A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.
- Hao Lu, Meng Tiak Toh, V. Narasimhan, S. Thamilselvam, S. Choksi, S. Roy
- Biology, Medicine
- Developmental biology
- 15 January 2015
Cilia perform a variety of functions in a number of developmental and physiological contexts, and are implicated in the pathogenesis of a wide spectrum of human disorders. While the ciliary axoneme… Expand