Hao-Hueng Chang

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OBJECTIVE To assess the effects of epigallocatechin-3-gallate (EGCG) on oncostatin M (OSM)-induced CCL2 synthesis and the associated signaling pathways in human osteoblastic cells. The therapeutic effect of EGCG on collagen-induced arthritis (CIA) in rats was also studied. METHODS CCL2 and c-Fos messenger RNA expression was analyzed by Northern blotting.(More)
OBJECTIVES The aim of this retrospective study was to assess systematically the case distribution among three types of mini-implants and to evaluate the clinical factors that influence the failure rates of mini-implants used as an orthodontic anchorage. MATERIAL AND METHODS Data for 359 mini-implants (miniplates, miniscrews, and microscrews) in 129(More)
OBJECTIVES Ectopic mandibular third molar is a rare condition, and information is limited about its causes and characteristics. This article reports a case of ectopic mandibular third molar and reviews the literature on the clinical signs and symptoms and management of this condition. STUDY DESIGN We report a case of an impacted mandibular third molar(More)
BACKGROUND/PURPOSE Dental pulp stem cells (DPSCs) have been proposed as a promising source of stem cells in nerve regeneration due to their close embryonic origin and ease of harvest. The aim of this study was to evaluate the efficacy of dopaminergic and motor neuronal inductive media on transdifferentiation of human DPSCs (hDPSCs) into neuron-like cells.(More)
BACKGROUND Connective tissue growth factor (CTGF/CCN2), associated with multiple human fibrotic diseases, is overexpressed in the tissue of gingival overgrowth. Although surgical excision is the current treatment modality for gingival overgrowth, the recurrent rate is high despite proper recall programs. Thrombin plays a key role in wound repair,(More)
OBJECTIVES The aim of this retrospective study was to evaluate systematically the potential factors that influence failure rates of temporary anchorage devices (TADs) used for orthodontic anchorage. MATERIALS AND METHODS Data on 492 TADs (miniplates, pre-drilling miniscrews, and self-drilling miniscrews) in 194 patients were collected. The factors related(More)
OBJECTIVES The issue of existence of malignancy within oral leukoplakia has seldom been addressed in Taiwan. The aims of this study were to investigate the prevalence of carcinoma and dysplasia within oral leukoplakia at the time of clinical diagnosis and to identify the associated risk factors in Taiwan. STUDY DESIGN The prevalence rate of malignancy and(More)
OBJECTIVES The aim of the study was to investigate the effectiveness of an educational program on the reduction of the incidence of wrong-site tooth extraction at the outpatient department of a university hospital in Taiwan. STUDY DESIGN Data collected from cases of wrong-site tooth extraction during 1996 to 1998 were used to develop a specific(More)
BACKGROUND Although several previous studies have compared the efficacy of Gow-Gates mandibular block (GGMB) and inferior alveolar nerve block (IANB), the results remain controversial. This study used an objective, standardized and precise protocol to evaluate and compare the effectiveness and success rate of GGMB and IANB. METHODS The study group(More)
BACKGROUND/PURPOSE Although exhaustively studied, the mechanism responsible for tooth support and the mechanical properties of the periodontal ligament (PDL) remain a subject of considerable controversy. In the past, various experimental techniques and theoretical analyses have been employed to tackle this intricate problem. The aim of this study was to(More)