Hao Guo

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GSK3β genotypes may interact with major depressive disorder (MDD) and may have a role in determining regional gray matter volume differences from healthy comparison subjects. However, any associations of GSK3β genotypes with MDD related to abnormal functional brain activity have yet to be elucidated. In the present study, resting state functional brain(More)
BACKGROUND Neuron loss, glial activation and vascular degeneration are common sequelae of ischemia-reperfusion (I/R) injury in ocular diseases. The present study was conducted to explore the ability of curcumin to inhibit retinal I/R injury, and to investigate underlying mechanisms of the drug effects. METHODOLOGY/PRINCIPAL FINDINGS Different dosages of(More)
BACKGROUND The NADH-ubiquinone oxidoreductase flavoprotein gene (NDUFV2), which encodes a 24 kD mitochondrial complex I subunit, has been reported to be positively associated with schizophrenia and bipolar disorder in different populations. METHODS We genotyped the promoter variants of this gene (rs6506640 and rs1156044) by direct sequencing in 529(More)
Worms can spread throughout the Internet very quickly and are a great security threat. Constant quarantine strategy is a defensive measure against worms, but its reliability in current imperfect intrusion detection systems is poor. A pulse quarantine strategy is thus proposed in the current study. The pulse quarantine strategy adopts a hybrid intrusion(More)
Depression is closely linked to the morphology and functional abnormalities of multiple brain regions; however, its topological structure throughout the whole brain remains unclear. We collected resting-state functional MRI data from 36 first-onset unmedicated depression patients and 27 healthy controls. The resting-state functional connectivity was(More)
Internet worm attacks reduce network security and cause economic losses. The use of a quarantine strategy is prominent in defending against worms, and it has been applied to various worm propagation models. Although theoretical analysis suggests that worms must get eliminated under quarantine, such a result does not appear in a real network. The time delay(More)
  • Bahareh Sadat Arab, Dieter Gawlick, Venkatesh Radhakrishnan, Hao Guo, Boris Glavic
  • 2014
We present an architecture and prototype implementation for a generic provenance database middleware (GProM) that is based on the concept of query rewrites, which are applied to an algebraic graph representation of database operations. The system supports a wide range of provenance types and representations for queries, updates, transactions, and operations(More)
Resting state functional brain networks have been widely studied in brain disease research. However, it is currently unclear whether abnormal resting state functional brain network metrics can be used with machine learning for the classification of brain diseases. Resting state functional brain networks were constructed for 28 healthy controls and 38 major(More)