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Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China
It is concluded that actinomycetes isolated from mangrove habitats are a potentially rich source for the discovery of anti-infection and anti-tumor compounds, and of agents for treating neurodegenerative diseases and diabetes. Expand
Characterization and Online Detection of Surfactin Isomers Based on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of Nitric Oxide and the Release of TNF-α and IL-6 in
It was revealed that the surfactin isomers showed strong inhibitory properties on the overproduction of nitric oxide and the release of IL-6 on LPS-induced murine macrophage cell RAW264, which will be very helpful for the development of this novel kind of natural product as new anti-inflammatory agents. Expand
Chemical constituents from endophytic fungus Fusarium oxysporum.
Beauvericin showed cytotoxicity against PC-3, PANC-1, and A549 with IC(50) value of 49.5 ± 3.8, and exhibited anti-bacterial activity towards methicillin-resistant Staphylococcus aureus and Bacillus subtilis. Expand
Two new sesquiterpenes and six norsesquiterpenes from the solid culture of the edible mushroom Flammulina velutipes
Abstract One new sesquiterpene with a novel carbon skeleton, flammulinol A (1), one new isolactarane sesquiterpene and six isolactarane-related norsesquiterpenes, flammulinolides A–G (2–8), as wellExpand
Steroidal saponins from Solanum nigrum.
Six new steroidal saponins, solanigrosides C-H (2-7), and one known saponin, degalactotigonin (1), were isolated from the whole plant of Solanum nigrum. Their chemical structures were elucidatedExpand
Polyphenols from wolfberry and their bioactivities.
Nine new phenylpropanoids, one new coumarin, and 43 known polyphenols were isolated from wolfberry, including their bioactivities including oxygen radical absorbance capacity (ORAC), and some compounds displayed DPPH radical scavenging activity. Expand
Bioactive sesquiterpenoids from the solid culture of the edible mushroom Flammulina velutipes growing on cooked rice.
The results suggest that the solid culture of F. velutipes on cooked rice could be a good functional food and the structures of new metabolites were elucidated by NMR experiments. Expand
Complete assignments of 1H and 13C NMR spectral data of nine surfactin isomers
A new surfactin isomer was isolated from a mangrove bacteria strain ‘Bacillus sp’, and full assignments of 1H and 13C NMR spectral data were achieved for the first time by a combination of mass spectrometry and 1D and 2D NMR experiments. Expand
The Anti-Oxidant and Antitumor Properties of Plant Polysaccharides.
The research progress of signaling pathways involved in the initiation and progression of oxidative stress- and cancer-related diseases in humans are reviewed and current problems and future directions for the application of those plant polysaccharides are listed and discussed. Expand
Bioactive iridoid glucosides from the fruit of Gardenia jasminoides.
Seven new iridoid glucosides isolated from the fruit of Gardenia jasminoides showed that compounds 4 and 6-12 can improve the short-term memory capacity to varying degrees, suggesting that these compounds may have a potential antagonism effect against Alzheimer's disease. Expand