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The proliferation of cardiac fibroblasts (CFs) and excessive deposition of extracellular matrix (ECM) are the main pathological characteristics of cardiac fibrosis. In recent years, microRNAs (miRNAs) have been found to be a new kind of regulator in cardiac fibrosis. The purpose of this study was to investigate the role of microRNA-9 (miR-9) in the process(More)
Hierarchical data structures are important for many computing and information science disciplines including data mining, terrain modeling, and image analysis. There are many specialized hierarchical data management systems , but they are not always available. Alternatively, relational databases are far more common and offer superior reliability,(More)
Urethral diverticula with calculi have a low incidence as reported in the literature. Diverticulum of female urethra is rare, often discovered due to associated complications. We report a case of diverticulum of the female urethra containing giant calculi in a 62-year-old multiparous woman. She consulted with our office due to dysuria and a hard, painful(More)
We propose, in this paper, to consider the problem of Web service antipatterns detection as a multi-objective problem where examples of Web service antipatterns and well-designed code are used to generate detection rules. To this end, we use multi-objective genetic programming (MOGP) to find the best combination of metrics that maximizes the detection of(More)
OBJECTIVE To use meta-analysis to determine the accuracy of percutaneous core needle biopsy in the diagnosis of small renal masses (SMRs ≤ 4.0 cm). MATERIALS AND METHODS Studies were identified by searching PubMed, Embase, and the Cochrane Library database up to March 2013. Two of the authors independently assessed the study quality using QUADAS-2 tool(More)
To improve the quality of software systems, one of the widely used techniques is refactoring, defined as the process of improving the design of an existing system by changing its internal structure without altering the external behavior. The majority of existing refactoring works do not consider the impact of recommended refactorings on the quality of(More)
Background. Although numerous studies have shown that plasma fibrinogen is linked to renal cell carcinoma (RCC) risk, the consistency and magnitude of the effect of plasma fibrinogen are unclear. The aim of the study was to explore the association between plasma fibrinogen and RCC prognosis. Methods. An electronic search of Embase, PubMed/MEDLINE, and the(More)
BACKGROUND Ki-67 is an established marker of cell proliferation, and the Ki-67 index correlates with the clinical course of several cancer types, including bladder cancer (BC). However, the clinicopathological and prognostic significance of Ki-67 in bladder cancer remains unclear. Therefore, we performed a systematic review and meta-analysis to clarify this(More)