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Translation termination at premature termination codons (PTCs) triggers degradation of the aberrant mRNA, but the mechanism by which a termination event is defined as premature is still unclear. Here… Continue Reading
MicroRNAs are endogenous approximately 21-nucleotide-long non-coding RNAs that act as post-transcriptional regulators of gene expression by base pairing to target mRNAs. Mature miRNAs form part of… Continue Reading