Hansjorg Danuser

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In the present study, the role of 5-HT(1A) receptors in control of lower urinary tract function in cats was examined using 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) as agonists and WAY100635 and LY206130 as antagonists. Bladder function was assessed using cystometric infusion of saline or 0.5% acetic(More)
1. 5-Hydroxytryptamine (5-HT) is intimately associated with central sympathetic and somatic control of the lower urinary tract. The sympathetic and somatic innervation of the lower urinary tract is conveyed through efferent axons of the hypogastric and pudendal nerves, respectively. 2. The present study examined the effects of(More)
Norepinephrine (NE)-containing terminals densely innervate sympathetic preganglionic neurons in the intermediolateral nucleus and somatic motor neurons in Onuf's nucleus that project through the hypogastric and pudendal nerves, respectively, to innervate the lower urinary tract. In the present study, we pharmacologically analyzed the role of noradrenergic(More)
OBJECTIVE The voluntary control of micturition is believed to be integrated by complex interactions among the brainstem, subcortical areas and cortical areas. Several brain imaging studies using positron emission tomography (PET) have demonstrated that frontal brain areas, the limbic system, the pons and the premotor cortical areas were involved. However,(More)
PURPOSE The purpose of the present study was to determine the peripheral neural pathways, spinal distribution, sizes, and peptide transmitter content of primary afferent and autonomic efferent neurons that innervate the prostate gland. METHODS Retrograde transport of the fluorescent dye "fast blue" (injected into the prostate gland) was combined with(More)
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