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The role played by cell addition, cell enlargement, and matrix deposition in the endochondral growth of the condyle was assessed in weanling rats by four approaches making use of the light microscope: morphometry, 3H-thymidine radioautography, 3H-proline radioautography, and immunostaining for the cartilage-specific type II collagen. From the articular(More)
AIM To investigate the mechanical, chemical and structural alterations of human root dentine following exposure to ascending sodium hypochlorite concentrations. METHODOLOGY Three-point bending tests were carried out on standardized root dentine bars (n = 8 per group, sectioned from sound extracted human third molar teeth) to evaluate their flexural(More)
Deviations in the growth of the mandibular condyle can affect both the functional occlusion and the aesthetic appearance of the face. The reasons for these growth deviations are numerous and often entail complex sequences of malfunction at the cellular level. The aim of this review is to summarize recent progress in the understanding of pathological(More)
OBJECTIVE Deviations in length and shape of tooth roots result from hard tissue resorption or occur as a developmental disorder. The purpose of this report is to present a type of root malformation which seems to have gone unreported so far. STUDY DESIGN Two patients showing severely dysplastic roots of all permanent first molars were evaluated using(More)
AIM To investigate the pulpal response to direct pulp capping in healthy human teeth with mineral trioxide aggregate (MTA) as against calcium hydroxide cement (Dycal) as control. METHODOLOGY Twenty healthy human third molars had iatrogenic pulpotomy and direct pulp capping with MTA. Another 13 teeth were capped with Dycal as controls. The teeth were(More)
The distal-less homeobox gene DLX3 is expressed in a variety of tissues including placenta, skin, hair, teeth, and bone. Mutation of DLX3 (c.571_574delGGGG) causes the tricho-dento-osseous syndrome (TDO), characterized by abnormal hair, teeth, and bone. Evaluation of a kindred segregating the DLX3 c.561_562delCT mutation revealed distinct changes in the(More)
Temporomandibular joints with normal and abnormal disc positions, obtained from 15 females and 38 males (most between 15 and 50 years of age), were examined under a light microscope. Histologic changes attributed to degeneration and remodeling of the articular tissues were graded according to their prominence and extension along the articular surfaces.(More)
Eight condyles of four growing monkeys (Macaca fascicularis) of estimated ages between 1.6 and 3.6 years (minimum and maximum) were analyzed using radioautographic, histometric, and stereologic techniques. The aim of the study was to examine the relationship between intracondylar variations in structure and growth activities. The animals received 3H-proline(More)
Serial intraoral photographs, radiographs, and ground sections from an extracted upper permanent canine served to characterize dental abnormalities in a 15-year-old girl suffering from severe (type III) osteogenesis imperfecta (OI) due to a point mutation that substituted glycine 688 of the alpha 2(I) chain of collagen I by serine. Dental records showed(More)
AIM To evaluate the effect of different root canal irrigating regimes on dentine penetration of Patent Blue dye. METHODOLOGY Eighty extracted single-rooted human mandibular premolar teeth with narrow root canals were prepared using ProFile instruments. After each instrument, canals were irrigated with 1% sodium hypochlorite. Subsequently, teeth were(More)