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Importance splitting is a simulation technique to estimate very small entrance probabilities for Markov processes by splitting sample paths at various stages before reaching the set of interest. This can be done in many ways, yielding different variants of the method. In this context, we propose a new one, called fixed number of successes. We prove… (More)

— The generalization of the sampling theorem to multidimensional signals is considered, with or without bandwidth constraints. The signal is modeled as a stationary random process and sampled on a lattice. Exact expressions for the mean square error of the best linear interpo-lator are given in the frequency domain. Moreover, asymp-totic expansions are… (More)

We present a simulation methodology for Bayesian estimation of rate parameters in Markov jump processes arising for example in stochastic kinetic models. To handle the problem of missing components and measurement errors in observed data, we embed the Markov jump process into the framework of a general state space model. We do not use diffusion… (More)

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