Hans-Peter Krüger

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RATIONALE Carbamazepine (CBZ) is known to produce cognitive side effects being at least partly relevant for driving. In contrast to this, the cognitive effects of oxcarbazepine (OXC) are suspected to be less pronounced. OBJECTIVE This study aimed to test 900 mg/day OXC as compared to 600 mg/day CBZ with respect to driving. METHODS Driving performance of(More)
Currently, it is unclear whether sleep attacks in Parkinson's disease (PD) represent a novel entity or just a phenomenon of daytime sleepiness. We investigated 10 PD patients with sleep attacks and compared them with 10 PD patients without any daytime sleepiness. The patients were matched according to their dopaminergic medication and subjected to a sleep(More)
Comparing drug-induced driving impairments with the effects of benchmark blood alcohol concentrations (BACs) is an approved approach to determine the clinical relevance of findings for traffic safety. The present study aimed to collect alcohol calibration data to validate findings of clinical trials that were derived from a representative test course in a(More)
Drivers on the road are constantly interacting. The development of new sensor, display and communication systems has laid the basis for ambient intelligence (AmI) technology in road traffic. The effects of such devices on driver behavior and emotional response have to be analyzed, e.g. by using driving simulator studies. By implementing the results of these(More)
We present a framework for ambient traffic in driving simulators. Each vehicle of the ambient traffic includes a model of a driver with a free configurable behaviour. The behaviour of the driver can be changed online during simulation. These behavioural models are loaded at runtime, so the framework can easily be updated to integrate special behaviour. The(More)
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