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An optimized coupled test system for glutathione peroxidase in red blood cells is presented. In the improved assay, tert. butyl hydro-peroxide was employed as an acceptor substrate at twenty times K m (app) concentration. By aid of a batching procedure for instant separation of hemoglobin from glutathione peroxidase, it could be proved that… (More)
Policy decisions to ratify recent climate policy agreements, as the Kyoto Protocol , rely on quantitative impact assessments, which are primarily based on applied economic modelling concepts. A crucial decision factor for politicians are the economic compliance costs of implementing binding emissions reduction targets. The Energy Modeling Forum (EMF)… (More)
The validation procedure for the process control system of a plant for the large scale production of human albumin from plasma fractions is described. A validation master plan is developed, defining the system and elements to be validated, the interfaces with other systems with the validation limits, a general validation concept and supporting… (More)
Intense heavy ion beam production with electron cyclotron resonance (ECR) ion sources is a common requirement for many of the accelerators under construction in Europe and elsewhere. An average increase of about one order of magnitude per decade in the performance of ECR ion sources was obtained up to now since the time of pioneering experiment of R. Geller… (More)
A detailed experimental and simulation study of the extraction of a 24 keV He(+) beam from an ECR ion source and the subsequent beam transport through an analyzing magnet is presented. We find that such a slow ion beam is very sensitive to space-charge forces, but also that the neutralization of the beam's space charge by secondary electrons is virtually… (More)
First results of the Instrumentation Line for the deep-sea ANTARES neutrino telescope Quantification of ion-induced molecular fragmentation of isolated 2-deoxy-D-ribose molecules 16 O from γ-ray angular distributions witha 4π-detector array Charge exchange emission from solar wind helium ions Astrophys.
Ion source development at KVI is focused on increasing the beam intensity from the electron cyclotron resonance ion source injector and optimizing the beam transport and injection into the superconducting AGOR cyclotron. We describe several modifications that have resulted in a significant performance increase of the ion source. We also present the first… (More)