Hans Jørgen Hynding Knudsen

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Chlamydia trachomatis infection is associated with severe Fallopian tube tissue damage leading to tubal infertility and ectopic pregnancy. To explore the molecular mechanisms behind infection an ex vivo model was established from human Fallopian tubes and examined by scanning electron microscopy and immunohistochemistry. Extensive tissue destruction(More)
PURPOSE Dysfunction of the epidermal growth factor (EGF) complex is essential to the growth and development of many human tumors. Overexpression of the EGF receptor (EGFR) is a characteristic finding in a considerable number of solid tumors and often signalizes poor prognosis. There is a major disagreement among researchers about both the frequency and(More)
The epidermal growth factor receptors, HER1, HER2, HER3 and HER4 play a key role in the growth of malignant tumors. The receptors of the EGF receptor family are not cancer-specific proteins since these receptors are expressed to some extent in both normal and benign tissue, but this is not elucidated in detail in ovarian tissue. High tumor-to-normal-tissue(More)
The purpose of the present investigation was to evaluate changes in contraceptional habits or sexual activity among adolescents as a consequence of the AIDS-campaigns. In 1986 and 1993 all pupils in their ninth school year in the municipality of Viborg answered an identical questionnaire concerning the mentioned subjects. Both in 1986 and 1993 one third had(More)
The study compares survival and complications during two periods with a different approach to radical hysterectomy as treatment of cervical cancer stages Ib and IIa. Group A included 128 patients operated during the years 1983-87. In that period 5 of the patients who were offered radical hysterectomy had cervical cancer stage IIa. Group B included 135(More)
A case report of an ectopic pregnancy in a non-communicating, undescended fallopian tube. A rare embryological development-failure is described, consisting of a right hemiuterus, a remotely located noncommunicating left fallopian tube and undescended left ovary associated with agenesis of the left kidney. A noncommunicating fallopian tube should be removed(More)
We present a case of infertility due to a “forgotten” IUD. Users of intrauterine devices are reported to have an increased risk of frank or subclinical genital infections which later may be the cause of infertility [1, 2]. Other mechanisms of causing infertility are possible. During the last two years we have seen three infertile patients with an IUD in(More)
OBJECTIVE To determine whether the HLA alleles DR1, DR3, DR4 and DR10 which have been suggested to be risk markers for unexplained recurrent miscarriages also play a part in women with recurrent miscarriages with Müllerian uterine fusion anomalies. STUDY DESIGN HLA-DR typing was undertaken in 28 women with recurrent miscarriage who had been surgically(More)
The purpose of the present paper was to investigate the influence of the AIDS-campaigns on adolescents' knowledge of contraception and pregnancy and their sources of information. All pupils in their ninth school year in the municipality of Viborg answered an identical questionnaire in 1986 and 1993, dealing with the mentioned subjects. In 1986, 539(More)