Hans-Georg Schlosser

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BACKGROUND During neurosurgery intraoperative imaging of vital neural structures on a cellular level would facilitate the development of new strategies for diagnosis and treatment. In vivo imaging would permit the detection of the tumour centre and infiltration zone. With targeted biopsies the lesion of interest could be determined before performing the(More)
The combination of galvanic labyrinth polarization and transcranial Doppler ultrasound was employed to depict the neurovascular coupling in the cerebral vestibular areas. For galvanic stimulation, surface electrodes were attached to the right and left mastoid and two further electrodes were fixed near to each shoulder blade. Thus, each pair of electrodes(More)
OBJECTIVE Hydrostatic devices have considerable advantages compared to "conventional" differential-pressure-valves concerning overdrainage, but are thought to imply a tendency to underdrain or to clog. The aim of this study was to evaluate the ability of the hydrostatic gravitational Dual-Switch-Valve (DSV) to minimize overdrainage-related complications(More)
Although intracranial hemorrhage has frequently been found responsible for mortality in adult patients with Alagille syndrome (AGS), no specific underlying cause has been identified. We describe the case of severe subarachnoid hemorrhage in a 30-year-old woman harboring five intracranial aneurysms and multiple peripheral vascular anomalies. To evaluate a(More)
BACKGROUND While strong vestibular input to the fastigial nucleus has been demonstrated, little is known on how this is integrated in the oculomotor region of the caudal area of fastigial nucleus. In this study, single units in the caudal region of the fastigial nucleus were recorded in the rat, while applying sinusoidal galvanic stimuli to the labyrinths.(More)
OBJECTIVE To evaluate the reliability of the gravitation-assisted adjustable proGAV shunt system with a prospective multicenter study conducted in 10 German hospitals. METHODS Enrollment for this observational study began in April 2005 and concluded in February 2006. The protocol required re-examinations 3 and 6 months postoperatively and fixed the(More)
Binocular eye movement responses to galvanic vestibular stimulation were measured in comatose patients. Healthy persons have been demonstrated to show a consistent and reproducible relationship between eye movement and galvanic vestibular stimulation. Any pathology of the vestibular integrating structures (brainstem and to some degree the cerebellum and(More)
Severe head injury (SHI) leads to systemic immunosuppression, which is processed by central mechanisms and is associated with a high risk of pneumonia. The timely identification of an immunodepressed condition in SHI patients might help prevent infections by changing the intensive care strategy. The aim of this prospective study is to evaluate a new method(More)
INTRODUCTION Based on the knowledge that traumatic brainstem damage often leads to alteration in brainstem functions, including the vestibulo-ocular reflex, the present study is designed to determine whether prediction of outcome in the early phase after severe traumatic brain injury is possible by means of vestibulo-ocular monitoring. METHODS(More)