Hans G. Stampfer

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Averaged and single sweep auditory event-related potentials (ERPs) were analysed in the time and frequency domain to demonstrate a dynamic, functional relationship between prestimulus EEG activity and poststimulus ERP changes. Evidence is presented of prestimulus "preparation changes" which were elicited by the presentation of regular, frequent target(More)
A combined analysis procedure was used to study auditory, sensory evoked potentials (EPs) and event-related potentials (ERPs) in human subjects. Single sweep and averaged data were analysed in the time and frequency domains. Recognised peaks, seen in the averaged data, were related to specific poststimulus changes within conventional delta, theta and alpha(More)
A critical appraisal is made of the evidence that depression is a causal risk factor for coronary heart disease. PubMed and Science Citation Index were searched for relevant papers. Forty eight papers satisfying inclusion criteria and reporting an association between a measure of depression and a coronary disease outcome were compared in terms of baseline(More)
A theory is proposed that "negative symptoms", which are usually associated with schizophrenia, are manifestations of a traumatic stress disorder that is fundamentally similar in terms of the clinical phenomena and pathophysiological disturbance to chronic post-traumatic stress disorder (PTSD) as defined in DSM-III-R. Wider theoretical implications are(More)
An overview of clinical trials can reveal a class effect on mortality that is not apparent from individual trials. Most large trials of lipid pharmacotherapy are not powered to detect differences in mortality and instead assess efficacy with composite cardiovascular endpoints. We illustrate the importance of all-cause mortality data by comparing survival in(More)
The 12-month outcome of 103 elderly depressed patients treated by psychiatrists in Perth, Western Australia, was good in 32-47% of cases, depending upon the stringency of the outcome criteria used. A higher than expected mortality was found, especially in men. No clear association was found between 12-month outcome and a variety of clinical variables at(More)
An impulse response hypothesis for evoked potentials is tested. The auditory evoked potential (AEP) is shown to be the consequence of an impulse (the arrival of sensory signals in cortex) giving rise to an impulse response (the resonation of electrocortical activity in the form of group linear waves). To demonstrate this, pre- and post-stimulus EEG activity(More)
Elderly patients with early-onset and late-onset depressive illness presenting to psychiatrists for treatment were compared for social, demographic, and clinical measures. For most factors measured no statistically significant differences were found. In the early-onset cases, patients were significantly more severely depressed. There was some evidence for(More)
The rates of admissions in 1976-78 to all hospitals in Western Australia, both psychiatric and non-psychiatric, of patients with a primary psychiatric diagnosis were analysed specifically for country of birth and whether they lived in Perth or in country areas. Eastern European migrants had the highest hospitalization rates, and Southern European migrants(More)
The few available longitudinal studies of depressive illness in the elderly indicate a poor prognosis. Various risk factors are discussed. Both severe and chronic physical illness, and severity of the depressive disorder are the two most important prognostic factors. The possibility of interactional effects between these risk factors should be studied. Most(More)