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by ITU-T is of significant importance since for the first time the same codec is adopted for wireless as well as wireline services. AMR-WB uses an extended audio bandwidth from 50 Hz to 7 kHz and gives superior speech quality and voice naturalness compared to existing second-and third-generation mobile communication systems. The wideband speech service(More)
The murine embryonal stem (ES) cell virus (MESV) can express transgenes from the long terminal repeat (LTR) promoter/enhancer in undifferentiated ES cells, but expression is turned off upon differentiation to embryoid bodies (EBs) and hematopoietic cells in vitro. We examined whether a human immunodeficiency virus type 1-based lentivirus vector pseudotyped(More)
The ability of lentiviral vectors to transfer genes into human hematopoietic stem cells was studied, using a human immunodeficiency virus 1 (HIV-1)-derived vector expressing the green fluorescence protein (GFP) downstream of the phosphoglycerate kinase (PGK) promoter and pseudotyped with the G protein of vesicular stomatitis virus (VSV). High-efficiency(More)
OBJECTIVES Lentiviral vectors can transduce nondividing cells. As most haematopoietic stem cells (HSCs) are nondividing in vivo, lentiviral vectors are promising viral vectors to transfer genes into HSCs. DESIGN AND SETTING We have used HIV-1 based lentiviral vectors containing the green fluorescent protein (GFP) gene to transduce umbilical cord blood(More)
Human immunodeficiency virus type 1-based lentivirus vectors containing the green fluorescent protein (GFP) gene were used to transduce murine Lin(-) c-kit(+) Sca1(+) primitive hematopoietic progenitor cells. Following transduction, the cells were plated into hematopoietic progenitor cell assays in methylcellulose and the colonies were scored for GFP(More)
This paper describes a multi-rate codec family developed as a potential candidate for the GSM Adaptive Multi Rate (AMR) codec standard. The codec family consists of the GSM Enhanced Full Rate (EFR) codec [I] and lower bit-rate extensions thereof: The codec family consists of several codecs, i.e., modes that have different bit-rate partitionings between(More)
The Third Generation Partnership Project (3GPP) and European Telecommunications Standards Institute (ETSI) have carried out development and standardisation of a wideband speech codec for GSM and the third generation mobile communication WCDMA system since 1999. The Adaptive Multi-Rate Wideband (AMR-WB) codec algorithm was selected in December 2000, and the(More)
We present in this paper new methods for achieving high-quality wideband speech at low rates using the ACELP algorithm. Several innovations are introduced to optimize the quality and minimize the complexity of the coder. A multi-rate wideband speech encoding algorithm based on these techniques was recently selected by 3GPP as the standard for AMR-WB, and is(More)
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