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Objective—To determine long-term effects of insulin glargine on vascular function in patients with type 2 diabetes. Methods and Results—A total of 49 in vivo endothelial function tests, intrabrachial… Continue Reading
Methods: Male hepatocyte-specific Pten-deficient mice (AlbCrePten), which develop spontaneously steatohepatitis and HCC, fed Control Diet (CD) or High Fat Diet (HFD) were randomly divided between… Continue Reading
BACKGROUND AND AIMS Abnormal glucose metabolism and non-alcoholic fatty liver disease (NAFLD) are common in HIV-positive (HIV+) subjects but longitudinal data are lacking. We determined the natural… Continue Reading
Insulin resistance is associated with an increased risk of atherothrombotic vascular disease, but the mechanisms are poorly understood. We determined how insulin in vivo regulates platelet activation… Continue Reading