Hanne Halgreen

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The symptomatic effect of pancreatic enzyme substitution therapy was examined in a 4-week double-blind crossover study. Twenty patients, 11 with and 9 without steatorrhoea, were examined. Pancreatic steatorrhoea was reduced from a median of 24 g/day to 10 g/day by the enzyme therapy (P less than 0.01). No significant pain reduction was found in either of(More)
To diagnose fundic atrophic (type A) gastritis as part of the clinical investigation of various diseases or for epidemiologic purposes, a simple and reliable diagnostic test would be of great value. We studied circulating levels of pepsinogen A (PGA) and pepsinogen C (PGC) in 179 patients with fundic atrophic gastritis, 29 unselected patients with gastric(More)
[14C]Triolein and [3H]oleic acid are useful tracers of dietary triglycerides and free fatty acids. The combustion/liquid scintillation counting technique was found a practicable method of estimating the fecal activity of these tracers. When ingested with the nonabsorbable marker 51CrCl3, the fecal excretion of 14C and 3H could be estimated accurately from(More)
Development of esophageal varices, ascites, and hepatic nephropathy is among the major complications of cirrhosis. The presence of cirrhotic cardiomyopathy, which includes a left ventricular diastolic dysfunction (DD), seems to deteriorate the course of the disease and the prognosis. Increased stiffness of the cirrhotic heart may decrease the compliance and(More)
Pancreatic tissue from 16 post mortem kidney donors have been examined for the content of pepsinogens. A zymogen with electrophoretic mobility, isoelectric point and molecular weight equal to that of pepsinogen C of gastric origin was found in all specimens. A comparison between pepsinogen C extracted from pancreatic tissue and gastric mucosa demonstrated(More)
The aspartic protease progastricsin (EC is found in all parts of the mammalian stomach and has also been found extragastrically. In humans and monkeys, seminal fluid usually contains high concentrations of progastricsin. Using immunohistochemistry and in situ hybridization, we determined in this investigation the origin of seminal progastricsin to(More)
The diagnostic efficiency of estimating the faecal fat excretion and faecal fat concentration in uncontrolled 3-day collections was estimated from a prospective series of 87 consecutive patients. The diagnoses were established on the basis of morphologic criteria, and the assimilation was established from the faecal 14C-triolein/3H-oleic acid test. These(More)
The reproducibility of measuring 3-day faecal fat and weight in outpatients, in inpatients served a fixed diet, and in intake-excretion studies was estimated from 64 duplicate measurements. Qualitatively, no significant difference between the results of the three regimens was found. Quantitatively, however, the more controlled the regimen, the better the(More)
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