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The value of constituent data to the non-profit sector is higher than ever (Hagen, 2006). Yet for small nonprofit organizations in particular, collecting, maintaining, accessing, and summarizing constituent data remains a daunting and frustrating task. This research examines why this is so. Using case studies of two small nonprofit organizations, we(More)
Neural correlates of long-term sensitization of defensive withdrawal reflexes in Aplysia occur in sensory neurons in the pleural ganglia and can be mimicked by exposure of these neurons to serotonin (5-HT). Studies using inhibitors indicate that transcription is necessary for production of long-term facilitation by 5-HT. Several mRNAs that change in(More)
A 75-year-old female with a remote history of electroconvulsive-shock therapy and more recent care for psychotic depression died due to thromboembolic disease. Intranuclear inclusions were found to be widespread in her brain after autopsy. There was a paucity of the usual pathologic findings of herpes simplex virus (HSV) encephalitis, but light microscopic(More)
Biallelic inherited mutations in the oxidative DNA damage repair gene MUTYH predispose to colorectal adenomas and colorectal carcinoma (CRC) with high penetrance. We investigated whether rare inherited variants in other oxidative DNA damage repair genes predisposed to CRC. Single marker association analyses were assessed under an allelic model with(More)
PURPOSE Genome-wide association studies have identified numerous loci associated with colorectal cancer risk. Several of these have also been associated with patient survival, although none have been validated. Here, we used large independent training and validation cohorts to identify robust prognostic biomarkers for colorectal cancer. EXPERIMENTAL(More)
Purpose: Genome-wide association studies have identified numerous loci associated with colorectal cancer risk. Several of these have also been associated with patient survival, although none have been validated. Here, we used large independent training and validation cohorts to identify robust prognostic biomarkers for colorectal cancer. Experimental(More)
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