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Fibroblast growth factor receptor 3 is highly expressed in rarely dividing human type A spermatogonia
Human spermatogonia (Spg) and their fetal precursors express fibroblast growth factor receptor 3 (FGFR3). To further elucidate the role of FGFR3 in the control of Spg self-renewal, proliferation,Expand
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Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression
HIPK2 shows overlapping localization with p53 in promyelocytic leukemia (PML) nuclear bodies (PML-NBs) and functionally interacts with p53 to increase gene expression. Here we demonstrate that HIPK2Expand
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SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation
In this study, we characterize the molecular and functional features of a novel protein called SPOC1. SPOC1 RNA expression was previously reported to be highest in highly proliferating tissues andExpand
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PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3
PHF13 is a chromatin affiliated protein with a functional role in differentiation, cell division, DNA damage response and higher chromatin order. To gain insight into PHF13's ability to modulateExpand
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SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis
SPOC1 (PHF13) is a recently identified protein that has been shown to dynamically associate with somatic chromatin, to modulate chromatin compaction and to be important for proper cell division.Expand
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The PML domain of PML–RARα blocks senescence to promote leukemia
Significance Acute promyelocytic leukemia (APL) is a model for oncoprotein-targeted therapy because induced degradation of the promyelocytic leukemia protein–retinoic acid receptor (PML–RAR) fusionExpand
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