Hannah J. Haynie

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Protons are involved in gating Kir2.3. To identify the molecular motif in the Kir2.3 channel protein that is responsible for this process, experiments were performed using wild-type and mutated Kir2. 3 and Kir2.1. CO2 and low pHi strongly inhibited wild-type Kir2.3 but not Kir2.1 in whole cell voltage clamp and excised inside-out patches. This CO2/pH(More)
The notion that linguistic forms and meanings are related only by convention and not by any direct relationship between sounds and semantic concepts is a foundational principle of modern linguistics. Though the principle generally holds across the lexicon, systematic exceptions have been identified. These "sound symbolic" forms have been identified in(More)
1. Introduction Within the Gricean approach to pragmatics, it is commonly held that the principles of cooperative conversation only apply to the meaning of an utterance. With the exception of the maxim of Manner, which I set aside, the conversational maxims only make reference to 'what is said' in an utterance, not 'how it is said'. The first maxim of(More)
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