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The pathophysiological basis of acute-on-chronic liver failure (ACLF) is unclear but systemic inflammatory response is thought to be important. In patients with ACLF, the molecular adsorbents recirculating system (MARS) improves individual organ function, but the effect of MARS on the proposed mediators of systemic inflammatory response is unclear. The(More)
Nodular subcutaneous and generalized fat necrosis, due to rupture of a pancreatic cyst into the portal vein, occurred in a 57-year-old man. No report of a similar mechanism causing such a result was found in the literature. Multiple papular lesions, with microscopic changes in the skin, although not in themselves specific, should lead to a suspicion of(More)
A network of kinases, including WNKs, SPAK and Sgk1, is critical for the independent regulation of K+ and Na+ transport in the distal nephron. Angiotensin II is thought to act as a key hormone in orchestrating these kinases to switch from K+ secretion during hyperkalaemia to Na+ reabsorption during intravascular volume depletion, thus keeping disturbances(More)
Im klinischen Bereich ist beim kritisch kranken Patienten die Blutgasanalyse unverzichtbar. Auch in der Notfallmedizin bestehen möglicherweise absolute Indikationen für eine präklinische Blutgasanalyse (=BGA). Mit Hilfe der BGA kann eine Azidosepufferung bei der kardiopulmonalen Reanimation (CPR) bzw. beim kardiogenen Schock gezielt durchgeführt werden.(More)
During cardiopulmonary resuscitation, pH and base excess (BE) decrease to a variable degree due to metabolic acidosis. The main cause has been shown to be lactate, which cannot be eliminated sufficiently because of low perfusion during cardiac massage. Both BE and lactate can be measured in the prehospital phase. The aim of the study was to determine if BE(More)
BACKGROUND Fluid management guided by oesophageal Doppler monitor has been reported to improve perioperative outcome. Stroke volume variation (SVV) is considered a reliable clinical predictor of fluid responsiveness. Consequently, the aim of the present trial was to evaluate the accuracy of SVV determined by arterial pulse contour (APCO) analysis, using the(More)
UNLABELLED We evaluated the effects of aggressive warming and maintenance of normothermia on surgical blood loss and allogeneic transfusion requirement. We randomly assigned 150 patients undergoing total hip arthroplasty with spinal anesthesia to aggressive warming (to maintain a tympanic membrane temperature of 36.5 degrees C) or conventional warming (36(More)
BACKGROUND High concentrations of inspired oxygen are associated with pulmonary atelectasis but also provide recognized advantages. Consequently, the appropriate inspired oxygen concentration for general surgical use remains controversial. The authors tested the hypothesis that atelectasis and pulmonary dysfunction on the first postoperative day are(More)
UNLABELLED Prehospital blood gas analysis is a new method in out-of-hospital emergency care. In a prospective pilot study we evaluated the feasibility of prehospital compensation of severe acidosis relying on different monitoring systems to evaluate patients oxygen, carbon dioxide or acid-base status, respectively. METHODS With the help of arterial blood(More)
OBJECTIVE A new portable device for blood gas analyses (BGA) has been examined for prehospital application. METHODS After a 1 h introduction to the procedure, two physicians used the blood gas analyzer in the emergency medical system in Graz, Austria, for 7 months. The indications for prehospital BGA were prolonged cardiopulmonary resuscitation,(More)