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We investigate the applicability of an incompressible diffuse interface model for two-phase incompressible fluid flows with large viscosity and density contrasts. Diffuse-interface models have been used previously primarily for density-matched fluids, and it remains unclear to what extent such models can be used for fluids of different density, thereby(More)
OBJECTIVE Cardiac rehabilitation (CR) is pivotal in preventing recurring events of myocardial infarction (MI). This study aims to investigate the effect of a smartphone-based home service delivery (Care Assessment Platform) of CR (CAP-CR) on CR use and health outcomes compared with a traditional, centre-based programme (TCR) in post-MI patients. METHODS(More)
We investigate the wetting condition for diffuse-interface methods in the simulation of two-fluid flows with moving contact lines. A current method, which uses a surface-energy approach, is shown not to result in a slope of the interface that is consistent with the prescribed value of the contact angle. A geometric formulation is proposed that does result(More)
BACKGROUND Lifespace is a multidimensional construct that describes the geographic area in which a person lives and conducts their activities, and reflects mobility, health, and well-being. Traditionally, it has been measured by asking older people to self-report the length and frequency of trips taken and assistance required. Global Positioning System(More)
In this paper, a solution-adaptive algorithm is presented for the simulation of incompressible viscous flows. The framework of this method consists of an adaptive local stencil refinement algorithm and 3-points central difference discretization. The adaptive local stencil refinement is designed in such a manner that 5-points symmetric stencil is guaranteed(More)
BACKGROUND Many systematic reviews exist on the use of remote patient monitoring (RPM) interventions to improve clinical outcomes and psychological well-being of patients with heart failure. However, research is broadly distributed from simple telephone-based to complex technology-based interventions. The scope and focus of such evidence also vary widely,(More)
A new heart rate variability (HRV) analysis method, quantifying the variation of nonlinear dynamic pattern (VNDP) in heart rate series, is proposed and validated against the age stratified Fantasia database. The method is based on three processes: (1) a recurrence quantification analysis (RQA) to quantify the dynamic patterns, (2) the use of mutual(More)
BACKGROUND Males experience a shorter life expectancy and higher rates of chronic diseases compared to their female counterparts. To improve health outcomes among males, interventions specifically developed for males that target their health behaviors are needed. Information technology (IT)-based interventions may be a promising intervention approach in(More)
BACKGROUND Compared to females, males experience higher rates of chronic disease and mortality, yet few health promotion initiatives are specifically aimed at men. Therefore, the aim of the ManUp Study is to examine the effectiveness of an IT-based intervention to increase the physical activity and nutrition behaviour and literacy in middle-aged males (aged(More)
Galangin can suppress hepatocellular carcinoma (HCC) cell proliferation. In this study, we demonstrated that galangin induced autophagy by activating the transforming growth factor (TGF)-β receptor/Smad pathway and increased TGF-β receptor I (RI), TGF-βRII, Smad1, Smad2, Smad3 and Smad4 levels but decreased Smad6 and Smad7 levels. Autophagy induced by(More)