Hanan M M Khalil

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Pulmonary embolism (PE) is the leading cause of maternal mortality in the developed world. Mortality from PE in pregnancy might be related to challenges in targeting the right population for prevention, ensuring that diagnosis is suspected and adequately investigated, and initiating timely and best possible treatment of this disease. Pregnancy is an example(More)
AIMS With the increase in the number of systematic reviews available, a logical next step to provide decision makers in healthcare with the evidence they require has been the conduct of reviews of existing systematic reviews. Syntheses of existing systematic reviews are referred to by many different names, one of which is an umbrella review. An umbrella(More)
PURPOSE To determine if changing from 1.5T to 3T breast magnetic resonance imaging (MRI) is associated with a change in BI-RADS categories, positive predictive value of biopsy recommendation, or cancer detection rates in high-risk screening breast MRI. MATERIALS AND METHODS Institutional Review Board (IRB) approval was obtained for this Health Insurance(More)
Reviews of primary research are becoming more common as evidence-based practice gains recognition as the benchmark for care, and the number of, and access to, primary research sources has grown. One of the newer review types is the 'scoping review'. In general, scoping reviews are commonly used for 'reconnaissance' - to clarify working definitions and(More)
There currently is no cure or established preventative treatment for Alzheimer's disease (AD). Considering the increasing aging population and the subsequent high prevalence of AD worldwide, identifying a cost-effective way to prevent AD is an essential unmet medical need. Relative to healthy human brain samples, postmortem AD brain samples have been shown(More)
OBJECTIVE The purpose of this article is to determine the underestimation rate of high-risk lesions diagnosed at MRI-guided breast biopsy. MATERIALS AND METHODS This was a retrospective review of 446 MRI-guided breast biopsies from January 2006 through December 2010. Data were collected on examination indication, lesion size and type, and pathology(More)
Background Fear of falling (FOF) is an important risk indicator for health-related outcomes and quality of life in patients with multiple sclerosis (MS). However, factors associated with FOF in MS are not well investigated. Objectives This study was done to explore predictors of FOF in this population. Methods Seventy relapsing remitting patients with(More)
PURPOSE Physiotherapists frequently prescribe home exercise programmes for individuals with Parkinson's disease (PD) and Huntington's disease (HD); however, little is known about clients' perceptions of such programmes and any barriers that may affect participation and compliance. METHOD A qualitative design was used to capture the attitudes and(More)
PURPOSE To investigate the capacity of a single triaxial accelerometer sensor in detecting gait and balance impairments in pre-manifest and manifest Huntington's disease (HD) subjects. METHODS Fourteen manifest HD (MHD) (age: 51.83±14.8), ten pre-manifest HD (PHD) (age: 44.8±11.7) and ten healthy subjects (HLY) (age: 56.4±10.9) were recruited. The sensor(More)
BACKGROUND Clinical intervention trials in people with Huntington disease (HD) have been limited by a lack of reliable and appropriate outcome measures. OBJECTIVE The purpose of this study was to determine the reliability and minimal detectable change (MDC) of various outcome measures that are potentially suitable for evaluating physical functioning in(More)