Hanan Hassan Omar

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We report the characterisation of the first neuropeptide receptor from the phylum Platyhelminthes, an early-diverging phylum which includes a number of important human and veterinary parasites. The G protein-coupled receptor (GPCR) was identified from the model flatworm Girardia tigrina (Tricladida: Dugesiidae) based on the presence of motifs widely(More)
Many neuropeptide transmitters require the presence of a carboxy-terminal alpha-amide group for biological activity. Amidation requires conversion of a glycine-extended peptide intermediate into a C-terminally amidated product. This post-translational modification depends on the sequential action of two enzymes (peptidylglycine alpha-hydroxylating(More)
OBJECTIVE To determine the effect of thickness of porcelain veneers constructed from CAD-CAM on their final color when two resin cements were used. METHODS Buccal surfaces of extracted sound human molars with shade 3M2 [verified using digital spectrophotometer (Vita Easyshade-Vident)] were reduced to expose flat enamel surfaces. CAD-CAM blocks (Vitablokcs(More)
Geldanamycin and its derivative 17AAG [17-(Allylamino)-17-demethoxygeldanamycin, telatinib] bind selectively to the Hsp90 chaperone protein and inhibit its function. We discovered that these drugs associate with mitochondria, specifically to the mitochondrial membrane voltage-dependent anion channel (VDAC) via a hydrophobic interaction that is independent(More)
This study evaluated the ability of two self-etching adhesives (a two-step and a one-step) and a conventional 3-step adhesive to bond composite to both intact and caries-affected dentin with and without thermocycling. Thirty extracted human teeth with occlusal caries were randomly assigned to three groups according to the adhesive used: Scotchbond(More)
PURPOSE Patients with epilepsy may exhibit changes in thyroid hormone balance, lipids and lipoproteins concentrations. The suggestion that lipid abnormalities are associated with subclinical thyroid dysfunction remains controversial. The aim of this study was to analyze whether thyroid dysfunction encountered in patients with epilepsy would also be(More)
PURPOSE The aim of this study was to determine the efficacy of new light-emitting diode (LED) curing units in the hardening of Class II composite restorations. METHODS AND MATERIALS Disk specimens 2 mm in diameter and 2.5 mm thick were prepared from 2 composites (Vit-l-escence, shade A3, Ultradent; Herculite XRV, shade A2, Kerr) in the following manner.(More)
BACKGROUND The continuous increase in number of people living with HIV/AIDS (PLWHA) represents a serious health and economic burden. HIV positive individuals with oral lesions have significantly lower oral health-related quality of life than HIV positive individuals without oral lesions. The objective of this study was to assess the knowledge, attitude and(More)
Health economics, a special branch of science applying economic principles to the health delivery system, is a relatively young subdiscipline. The literature is scanty about teaching health economics in the medical and dental fields. Delivery methods of this topic vary from one university to another, with lectures, seminars, and independent learning(More)
Objectives: To examine the validity and reliability of the Jefferson Scale of Empathy-Health Care Provider Student version (JSE-HPS) in a sample of dental students in Malaysia, with the secondary aim of assessing empathy levels in first to final year dental students in public and private universities in Malaysia. Methods: The JSE-HPS was administered to 582(More)