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Candidatus Neoehrlichia mikurensis infection identified in 2 hematooncologic patients: benefit of molecular techniques for rare pathogen detection.
- S. Pekova, J. Vydra, +7 authors T. Kozák
- Medicine, Biology
- Diagnostic microbiology and infectious disease
- 1 March 2011
Using 16S rDNA sequencing and transmission electron microscopy, 2 lymphoma patients infected with Candidatus Neoehrlichia mikurensis are identified and the clinical presentation suggested ehrlichiosis-like syndrome. Expand
Characterization of Two Historic Smallpox Specimens from a Czech Museum
Two complete variola virus genomes from human tissues kept in a museum in Prague dating back 60 and 160 years are determined, showing that the 60-year-old specimen was most likely an importation from India, a country with endemic smallpox at that time. Expand
Borna disease virus (BDV) circulating immunocomplex positivity in addicted patients in the Czech Republic: a prospective cohort analysis
Investigating the seropositivity of BDV circulating immunocomplexes (CIC) in patients with alcohol and drug dependence and healthy individuals (blood donors) found no association between BDV CIC positivity and other anamnestic and demographic characteristics. Expand
Borna disease virus circulating immunocomplex positivity and psychopathology in psychiatric patients in the Czech Republic.
The highest levels of BDV CIC were detected in patients with more severe psychopathology, and this was associated with the higher severity of psychopathology in comparison with patients with mild or moderate psychopathology. Expand
Induction and characterization of a replication competent cervid endogenous gammaretrovirus (CrERV) from mule deer cells.
For the first time induction of replication competent CrERV by cocultivation of deer and human cells is described and the physical properties and tropism of the induced virus are characterized. Expand
Sodium Valproate Facilitates the Propagation of Granulocytic Ehrlichiae (Anaplasma phagocytophilum) in HL-60 Cells
NaVPA can facilitated continuous propagation of granulocytic ehrlichiae in cell cultures without a substantial loss of infectiveness, and was proved to prove whether sodium valproate, a salt of di-n-propylacetic acid (VPA) known to trigger cellular differentiation in several solid and hematopoietic malignancies is similarly efficient in eHRlichial cultures. Expand
Exosomes released by imatinib‑resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib‑sensitive cells in the presence of imatinib.
- Tereza Hrdinova, O. Toman, +13 authors J. Petrak
- International journal of oncology
- 23 December 2020
It is suggested that exosomes and their respective candidate surface proteins could be potential diagnostic markers of TKI drug resistance in CML therapy. Expand
BSL3-4 agents in the Czech National Museum depository and their value forthe study of these organisms