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Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters.
  • Han Yu, I. Kim, K. Rice
  • Biology, Chemistry
    Journal of medicinal chemistry
  • 14 April 2004
TLDR
In their efforts toward developing a nonselective ligand that would block the effects of stimulants such as methamphetamine at dopamine, serotonin, and norepinephrine transporters, a series of 3-(3,4-dichlorophenyl)-1-indanamine derivatives were synthesized.
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones.
1,4-dihydropyrazolo[4,3-d]imidazole phenyl derivatives: a novel type II Raf kinase inhibitors.
Inhibition of GluN2A-Containing N-Methyl-d-Aspartate Receptors by 2-Naphthoic Acid
TLDR
The reaction mechanisms derived provide quantitative insight into the inhibitory mechanism of NPA and help anticipate its effects on GluN1/GluN2A receptors during both physiologic and pathologic activation modalities.
Synthesis and biological activity of 8beta-substituted hydrocodone indole and hydromorphone indole derivatives.
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