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We tackle a new challenge of modeling a perceptual experience in which a stimulus in one modality gives rise to an experience in a different sensory modality, termed synesthesia. To meet the challenge, we propose a probabilistic framework based on graphical models that enables to link visual modalities and auditory modalities via natural language text. An(More)
We propose a probabilistic model for behavior-based malware detection that jointly models sequential data and class labels. Given labeled sequences (harmless/malicious), our goal is to reveal behavior patterns and exploit them to predict class labels of unknown sequences. The proposed model is a novel extension of supervised latent Dirichlet allocation with(More)
The induction of an interferon-induced antiviral state is a powerful cellular response against viral infection that limits viral spread. Here, we show that a preexisting antiviral state inhibits the replication of influenza A viruses in human A549 cells by preventing transport of the viral genome to the nucleus and that the interferon-induced MxA protein is(More)
To develop a robust classification algorithm in the adver-sarial setting, it is important to understand the adversary's strategy. We address the problem of label flips attack where an adversary contaminates the training set through flipping labels. By analyzing the objective of the adversary, we formulate an optimization framework for finding the label(More)
(−)-Epigallocatechin-3-gallate (EGCG) is the most abundant catechin in green tea. In this study, we found that hepatitis C virus (HCV) infection was significantly suppressed by EGCG in an HCV cell culture (HCVcc) system using a JFH1-GFP chimeric virus, with a 50 % effective concentration (EC50) of 17.9 μM. The inhibitory activity of EGCG was confirmed by(More)
A significant problem of Gaussian process (GP) is its unfavorable scaling with a large amount of data. To overcome this issue, we present a novel GP approximation scheme for on-line regression. Our model is based on a combination of multiple GPs with random hyperparameters. The model is trained by incrementally allocating new examples to a selected subset(More)
Collapsed Gibbs sampling is a frequently applied method to approximate intractable inte-grals in probabilistic generative models such as latent Dirichlet allocation. This sampling method has however the crucial drawback of high computational complexity, which makes it limited applicable on large data sets. We propose a novel dynamic sampling strategy to(More)
The explosive amount of malware continues their threats in network and operating systems. Signature-based method is widely used for detecting malware. Unfortunately, it is unable to determine variant malware on-the-fly. On the hand, behavior-based method can effectively characterize the behaviors of malware. However, it is time-consuming to train and(More)