Han-Sheng Chuang

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Degeneration is a senescence process that occurs in all living organisms. Although tremendous efforts have been exerted to alleviate this degenerative tendency, minimal progress has been achieved to date. The nematode, Caenorhabditis elegans (C. elegans), which shares over 60% genetic similarities with humans, is a model animal that is commonly used in(More)
We demonstrate a new hybrid optoelectric technique that can manipulate objects across several length scales. The technique leverages a variety of different physical mechanisms to achieve the dynamic manipulation of droplets and also the in situ concentration of colloidal particles suspended in the droplets. Various physical mechanisms such as(More)
We demonstrate for the first time the dielectrophoretic trapping and manipulation of a whole animal, the nematode Caenorhabditis elegans. We studied the effect of the electric field on the nematode as a function of field intensity and frequency. We identified a range of electric field intensities and frequencies that trap worms without apparent adverse(More)
This study combined optical diffusometry and bead-based immunoassays to develop a novel technique for quantifying the growth of specific microorganisms and achieving rapid AST. Diffusivity rises when live bacteria attach to particles, resulting in additional energy from motile microorganisms. However, when UV-sterilized (dead) bacteria attach to particles,(More)
Worldwide Interoperability for Microwave Access (WiMAX) is one of the next generation broadband wireless access technologies. The WiMAX features longer transmission distance and more accomplished support of Quality of Service (QoS) than other wireless access technologies such as IEEE 802.11. Specifically, QoS has become an important role in the context of a(More)
Caenorhabditis (C.) elegans is an intriguing model animal. Often times, researchers may need to silence the squirming worms and brought them to various measurements. Here we present a method to rapidly silence the tiny animal by sublethal light-induced heat in a special microfluidic chip. The worm's neural functions are temporarily shut down when a(More)
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