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Circular dichroism study of enzymatic manipulation on magnetic and metallic DNA template nanowires.
Circular dichroism spectroscopy (CD) was used to examine the mechanism of endonuclease clipping and ligation of the DNA template nanowires. The biomolecular manipulation of the DNA template isExpand
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Examining MRI contrast in three-dimensional cell culture phantoms with DNA-templated nanoparticle chains.
DNA-templated nanoparticle (NP) chains were examined as potential magnetic resonance imaging (MRI) contrast agents using in vitro environments of the extracellular matrix and tissue. A 3-T clinicalExpand
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Circular dichroism study of the mechanism of formation of DNA templated nanowires.
In order to control the fabrication method, the mechanism used in the formation of DNA templated nanowires is investigated through circular dichroism (CD) spectroscopy. Metallic (Au) and magneticExpand
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Serial and parallel dip-pen nanolithography using a colloidal probe tip.
AFM tips terminated with PMMA colloids are used to pattern molecules in both serial and parallel modes by allowing the polymer on the tip to swell under different humidity conditions. This extensionExpand
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In vitro cytotoxic evaluation of metallic and magnetic DNA-templated nanostructures.
We evaluate the potential in vitro cytotoxicity that may arise from metallic and magnetic DNA-templated nanostructures. By using a fluorescence-based assay, the viability of cells was examined afterExpand
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Gold–iron oxide nanoparticle chains scaffolded on DNA as potential magnetic resonance imaging agents
We present a unique nanostructure design using DNA that can serve as potential magnetic resonance imaging (MRI) agents. By attaching gold and iron oxide NPs on linear strands of DNA, NP chains areExpand
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Transverse Relaxivity Changes after Layer-by-Layer Encapsulation of Multicomponent DNA Templated Nanostructures
We examine the effects on transverse proton relaxivity after layer-by-layer encapsulation of one-dimensional (1D), DNA templated nanostructures for potential applications as magnetic resonanceExpand
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Characterizing proton relaxation times for metallic and magnetic layer-by-layer-coated, DNA-templated nanoparticle chains.
Metallic and superparamagnetic DNA-templated nanoparticle (NP) chains are examined as potential imaging agents. Proton relaxation times (T(1) and T(2)) are measured for DNA nanostructures usingExpand
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Detecting DNA methylation through changes in transverse proton relaxation.
We present a facile, simple method to detect DNA methylation by measuring the transverse proton relaxation behaviour. Positively charged nanoparticles are arranged along the negatively chargedExpand
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Mechanism of proton relaxation for enzyme-manipulated, multicomponent gold-magnetic nanoparticle chains.
Longitudinal and transverse relaxation times of multicomponent nanoparticle (NP) chains are investigated for their potential use as multifunctional imaging agents in magnetic resonance imaging (MRI).Expand
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