Hamid Afshar

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OBJECTIVE This study aimed to evaluate the efficacy and safety of N-acetylcysteine, a glutamate-modulating agent, in patients with treatment-refractory obsessive-compulsive disorder as an adjunct to serotonin reuptake inhibitor treatment. METHODS Forty-eight patients (36 women; mean ± SD age, 30.93 ± 4.99) with obsessive-compulsive disorder who failed to(More)
Glutamate antagonists such as topiramate have been proposed based on the glutamate hypothesis of schizophrenia because its properties encourage its exploration and possible development as a medication for the treatment of schizophrenia. A randomised, double-blind, placebo-controlled clinical trial was performed on 18- to 45-year-old patients with(More)
We present the first example of a nontrivial higher spin theory in three-dimensional flat space. We propose flat-space boundary conditions and prove their consistency for this theory. We find that the asymptotic symmetry algebra is a (centrally extended) higher spin generalization of the Bondi-Metzner-Sachs algebra, which we describe in detail. We also(More)
OBJECTIVE Acceptance-based behavior therapy (ABBT) is a new psychotherapy for generalized anxiety disorder (GAD). The current study intended to compare severity of symptoms, worry and quality of life of GAD female patients between ABBT and control. METHODS This study was a randomized clinical trial. The sample included 18 women with GAD referred to(More)
BACKGROUND Coronary artery disease is the leading cause of death in industrialized countries and most patients with diabetes die from complications of atherosclerosis. The objective of this study was to determine the presence of diabetes mellitus and other conventional coronary heart disease risk factors (cigarette smoking, hypertension and hyperlipidemia)(More)
There is growing evidence that memantine, a noncompetitive N-methyl-d-aspartate receptor antagonist, may be applied as an add-on in treating patients suffering from obsessive–compulsive disorders (OCD). The aim of the present study was therefore to assess the effect of adjuvant memantine in a double-blind, randomized, and placebo-controlled study of the(More)
OBJECTIVES Limited evidence is available regarding mutual interactions between psychological factors and tooth loss. This study aimed to investigate the association between these two issues. METHOD In this 2011 cross-sectional study we obtained data from 4,585 adults who had completed information in 20 counties across Isfahan province, Iran, regarding(More)
A 91-year-old woman, presenting with flu-like symptoms, developed a brief episode of polymorphic ventricular tachycardia in the emergency department. The arrhythmia resolved spontaneously, and a subsequent electrocardiogram revealed Q waves and ST-segment elevation in the anterior precordial leads, along with a prolonged QT interval. The presumed diagnosis(More)
NTRODUCTION The purpose of this study was to examine alexithymia symptoms, demographic variables and the severity of gastrointestinal symptoms in a sample of patients with functional gastrointestinal disorders (FGID) and a comparative sample of healthy controls. MATERIALS AND METHODS The sample consisted of 237 individuals, 129 of whom were patients(More)
OBJECTIVE To investigate the relation between major depressive disorder and metabolic risk factors of coronary heart disease. INTRODUCTION Little evidence is available indicating a relationship between major depressive disorder and metabolic risk factors of coronary heart disease such as lipoprotein and apolipoprotein. METHODS This case-control study(More)