Hamid Abdollahi

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OBJECTIVES Motility plays a major role in pathogenicity of Helicobacter pylori, yet there is scarce data regarding its chemotactic behaviour. The present study was designed to investigate the chemotactic responses of local isolates of H. pylori towards various sugars, amino acids, as well as some other chemical substances. MATERIALS AND METHODS Chemotaxis(More)
BACKGROUND Clarithromycin resistance in Helicbacter pylori has been found to be associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to its ribosomal target or changing the site of methylation. The aim of this study was to determine the most important point mutations in 23s rRNA gene in H. pylori that are closely(More)
Radiotherapy (RT) is the most widely used cancer treatment modality that plays a pivotal role in the management of wide variety of cancers and malig-nancies. About 50% of all cancer patients receive radiation treatment during the course of their disease (1). Although by advances in medical technologies the final goal of RT, deliver the highest radiation(More)
BACKGROUND AND OBJECTIVES Alterations in CXCL10 (a Th1 chemokine) expression have been associated with various diseases. The aim of this study was to evaluate the serum CXCL10 levels in H. pylori-infected patients with peptic ulcer (PU), H. pylori-infected asymptomatic (AS) subjects and healthy H. pylori-negative subjects, and also to determine its(More)
BACKGROUND Antibiotic resistance is a major therapeutic problem in patients infected with Helicobacter pylori. H. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rRNA point mutations. OBJECTIVES In the present study, we investigated anti-mutational features of four traditionally Iranian(More)
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