Hamed Gouklani

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BACKGROUND Hepatitis B virus (HBV), hepatitis D virus (HDV), and human immunodeficiency virus (HIV) are transmitted by blood transfusion. Thus, hemodialysis (HD) patients are more prone to become the carriers of these infections due to their treatment demands. OBJECTIVES The aim of this study was to assess the prevalence of HBV and HIV infections among HD(More)
HIV-1 transmitted drug resistance (TDR) occurs when primary viruses bear drug resistance mutations (DRMs). TDR causes first-line antiretroviral (ARV) therapy (ART) failure and is becoming more pronounced due to the widespread use of ART. With the absence of routine individual-level drug resistance testing, the World Health Organization (WHO) recommends the(More)
BACKGROUND The E2 glycoprotein is an important encoded hepatitis C virus (HCV) protein that contains three different variable regions. OBJECTIVES The aim of the present study was to construct an HCV 1a/JFH1 chimeric virus by replacing the intergenotypic variable region (igVR) fragment of the highly variable region of the E2 gene of the Japanese Fulminant(More)
INTRODUCTION Mutation of the HBV precore gene prevents the production of HBeAg, which is an important target for immune responses. Distribution of this mutation varies along with frequency of HBV genotypes in accordance with geographic and ethnic variations. The general objective of this study was to evaluate the prevalence and characteristics of precore(More)
Introduction: Got safe loss syndrome (HIV) is represented with a variety of disorders of cellular and humoral immune dysfunction caused with personal immunodeficiency disease (HIV) infection. Immune deficiency caused by HIV, leads to opportunistic diseases & certainly the progression of the infections cause the patient's death. That is why we chose to(More)
Introduction: About 1/ 3 of the world crowd (2 billion) suffers from HBV infection. 15 to 40% of Hepatitis B cases develop into chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Considering the dangerous complication of the illness and the evidence that the prevalence is different in various areas of the country, this research was directed(More)
INTRODUCTION Manifestations of HBV infection differ in chronic and acute phases. Therefore, identifying the determinants such as mutations has a vital role in the treatment of the disease. A dual transversion in the basal core promoter (BCP) region is common among HBV patients. Thus, the present study was conducted with the objective of determining the(More)
Introduction: Hepatitis has involved many individuals and has left many complications. Hepatitis C is a type of hepatitis connected with several dilemmas. The purpose of the research is to study the Hepatitis epidemiology C into the Island of Qeshm in 2014. Method: this was an interventional study conducted on 1500 inhabitants of Qeshm Island. Participants(More)
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