Haluk Barbaros Oral

Learn More
Apoptosis induced by hydrogen peroxide (H 2 O 2) was investigated in Chinese hamster ovarian (CHO) cells, and compared to apoptosis induced by cisplatin (25 µM), a well-established apoptosis-inducing agent. In preliminary experiments, CHO cells were treated with low concentrations of H 2 O 2 (250-500 µM) continuously or for 3 hours, followed by washing and(More)
Brucellosis is a zoonotic disease that is still endemic in developing countries. Despite early diagnosis and treatment of patients, chronic infections are seen in 10-30% of patients. In this study, we aimed to investigate the immunological factors that play roles in the transition of brucellosis from acute infection into chronic infection. Here, more than(More)
Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus(More)
Although our knowledge about Brucella virulence factors and the host response increase rapidly, the mechanisms of immune evasion by the pathogen and causes of chronic disease are still unknown. Here, we aimed to investigate the immunological factors which belong to CD8+ T cells and their roles in the transition of brucellosis from acute to chronic(More)
The gastrointestinal tract is continuously exposed to foreign antigens such as those derived from food and microbiota of gut. Gut flora is an important entity of human body that plays crucial role in healthy immune system and various immuno-logical disorders. Exploration of interactions between gut flora and immune system is an important area of current(More)
  • 1