Hallvard Lilleng

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OBJECTIVES To investigate seasonal variation of migraine headache in a population residing in an extreme Arctic locale. BACKGROUND Exposure to light may trigger migraine attacks and patients may also be hypersensitive to light between the attacks. In previous studies of migraine in Northern latitudes we have demonstrated that patients with migraine(More)
OBJECTIVES In the vast majority of cases the cause for hypertension is not known. On the basis of observations from black and multiethnic populations, it has been hypothesized that a genetically high tissue creatine kinase activity may be an independent factor responsible for primary hypertension. If the relation between creatine kinase and blood pressure(More)
The correlation between creatine kinase (CK) and blood pressure (BP) was examined prospectively in 120 patients with persistent high CK and 130 individuals with normal CK. Hypertension was defined as systolic BP (SBP) ≥ 140 mm Hg or diastolic BP (DBP) ≥ 90 mm Hg or current use of antihypertensive medication. Baseline CK was weakly correlated with SBP (r =(More)
A 52 year old woman presented with neuropathic pain in both legs. Clinical neurological and neurophysiological examinations showed polyneuropathy, and a diagnostic work-up found no evidence of concomitant disorders or current drug use. She was treated with carbamazepin, but we stopped the drug because she had persistent dizziness. We started her on 400 mg(More)
Patients with difficult headaches referred from general practitioners to a neurology department in North Norway regularly complain of seasonal variation of headache. Svalbard, which comprises a number of islands located in the Arctic Ocean between Norway and the North Pole, is inhabited by approximately 2000 people and is one of the largest populated areas(More)
In this paper we report a patient with Parkinson's disease (PD) presenting with subacute motor symptoms, especially rigidity. The 75-year-old man had relatively moderate PD for 12 years, which was treated with levodopa until he developed marked rigidity. The rigidity became worse, with prolonged off-periods, despite treatment with increased doses of(More)
In this cross-sectional study we assessed the prevalence of hyperCKemia, defined as persistent CK values ≥210 U/L in women, ≥400 U/L in men <50 years and ≥280 U/L in men ≥50 years (reference values according to the Nordic Reference Interval Project). Blood samples were obtained from 12,828 participants in the 6th survey of The Tromsø Study. We identified(More)
BACKGROUND Laboratory reference intervals are not necessarily reflecting the range in the background population. This study compared creatine kinase (CK) reference intervals calculated from a large sample from a Norwegian population with those elaborated by the Nordic Reference Interval Project (NORIP). It also assessed the pattern of CK-normalization after(More)