Hallie Keller

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A survey of the prevalence of lung lesions in randomly selected slaughtered swine representative of the Swiss fattening pig population was carried out from May to September 1992 in six large abattoirs. In total 8921 lungs out of 561 herds were examined. Histological investigations were completed in every herd. No gross lesions could be found in 56% of the(More)
A case control study was designed to determine the risk factors for the reinfection of Swiss specific pathogen-free (SPF) pig herds with enzootic pneumonia. Detailed housing, management and environmental data were collected from 42 case farms and 50 control farms by means of a questionnaire. Factors with a significantly asymmetrical frequency distribution(More)
The pharmacokinetics of ascorbic acid were studied in 29 horses after intravenous (iv), subcutaneous, intramuscular (im) and oral administration. Following iv injection of 5 and 10 g ascorbic acid, respectively, a biphasic decline of ascorbic acid serum levels was found, indicating that the vitamin distributes in the body according to a two-compartment open(More)
Medical laboratory data are gained by scientific methods. The method-inherent uncertainties always produce an "inexactitude" of varying degree. The physician who uses these data as a support for his decisions should therefore be able to estimate the reliability of the laboratory data; this can be assessed by statistical methods. The most fundamental(More)
This study discusses the use of automatic image analysis equipment in quantifying the structural changes during growth of rat pulmonary parenchyma. At birth the latter consists of primary septa delineating a coarse structure of alveolar sacs which are then subdivided into alveoli by outgrowth of secondary septa from day 4 onwards. This process is followed(More)
It is current practice to record the performance of immunoassays by means of precision profiles (according to Ekins), in which the variation coefficient (relative standard deviation) is plotted against the analyte concentration. On the other hand, precision profiles are only occasionally used for evaluating the performance of conventional clinical-chemical(More)
White-cell count and differential blood count, total protein, lactate dehydrogenase activity (E.C. 1.1.1.27) and lactate concentration were determined in 496 CSF samples, obtained by lumbar puncture. Lactate was measured with a new enzymatic test. Reference values were determined for lactate and lactate dehydrogenase (90% limits: 1.2-2.1 mmol/l and 6-26(More)
We compared an enzyme immunoassay for T4 (MTPT4) developed in Halle with the Enzymun-Test T4, Boehringer Mannheim (BMT4). Calculated coefficients of correlation can not be used for interpretation of the two methods. By construction of Bias-profiles the evaluation of concentration depended precision and accuracy is possible. Both methods can be used equally(More)