Raşit Tükel4
Erhan Ertekin4
Erdem Tüzün3
Başar Bilgiç3
Learn More
This study investigated the association between the catechol-O-methyl transferase (COMT) Val158Met polymorphism and executive functions in 101 patients with obsessive-compulsive disorder (OCD) and 100 healthy-control subjects (HS). Results showed that there was no significant difference for the genotype distributions between the OCD and HS groups. OCD-Met(More)
A composite artificial neural network model is proposed to simulate the performance of the Wisconsin Card Sorting Test. The Wisconsin Card Sorting Test is a test of executive functions where prefrontal deficits are matched to some quantitative measures such as percentage of perseverative errors and number of failures to maintain set. In this work, the(More)
A connectionist model, which simulates the operation of prefrontal circuits during Stroop task is proposed. The Stroop test has traditionally been used as a measure of cognitive inhibition. The task is to inhibit an over-learned, habitual response (i.e., reading color words) in favor of an unusual, novel requirement (i.e., naming incongruously printed(More)
In the present study, we have tested the hypothesis that brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism is associated with obsessive-compulsive disorder (OCD) and also investigated the association between the BDNF Val66Met polymorphism and the performance on tests measuring executive functions in a sample of patients with OCD. A total(More)
The most reported event related potential (ERP) parameter during short-term memory retrieval has been P3 wave and the association has been built on the relation between P3 latency and reaction times. The aim of this study is to identify an ERP component that reflects the memory scanning process preceding the decision making stage which has been associated(More)
This study investigated episodic memory and metamemory for verbs and nouns in patients who have cognitive impairments associated with Parkinson's disease (PD). PD patients and healthy control participants were asked to recall word pairs and provide feeling-of-knowing (FOK) judgments for the items they were unable to recall. This was followed by a(More)
  • Duygu Gezen-Ak, Merve Alaylıoğlu, Gençer Genç, Ayşegül Gündüz, Esin Candaş, Başar Bilgiç +8 others
  • 2016
Vitamin D deficiency is suggested to be associated with Parkinson’s disease (PD). Our aim was to investigate the serum 25-hydroxyvitamin D3 (25OHD) levels of PD patients in Turkish cohort, to investigate any association of vitamin D binding protein (GC) genotypes with PD due to the significant role of GC in vitamin D transport, to determine whether vitamin(More)
OBJECTIVE In the present study, we investigate the association between the 5-HTTLPR polymorphism and executive functions in a sample of patients with obsessive compulsive disorder (OCD). METHOD A total of 98 unmedicated patients diagnosed with OCD according to DSM-IV criteria and 80 healthy controls were included in this study. The genotype frequencies of(More)
  • Arzu Çoban, Cem İsmail Küçükali, Başar Bilgiç, Nazlı Yalçınkaya, Hazal Haytural, Canan Ulusoy +7 others
  • 2014
BACKGROUND Anti-neuronal autoimmunity may cause cognitive impairment that meets the criteria for dementia. Objective. Our aim was to detect the incidence and clinical features of autoimmune encephalitis imitating clinical findings of primary dementia disorders and to delineate the validity of anti-neuronal antibody screening in dementia patients. METHODS(More)