Hakan Şarlak

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BACKGROUND Behçet's disease (BD), is a chronic, systemic vasculitis, which may affect all types and sizes of blood vessels. BD is associated with endothelial dysfunction and chronic inflammation. Endothelial dysfunction is the critical early step in the process of atherogenesis, and it is commonly investigated by measuring arterial stiffness. Mean platelet(More)
Psoriasis is associated with an increased risk of atherosclerosis. Endothelial dysfunction is the critical early step in the process of atherogenesis, and it is commonly investigated by measuring arterial stiffness. We aimed to investigate the relationship between arterial stiffness and high-sensitivity C-reactive protein (hsCRP) in patients with psoriasis.(More)
High levels of circulating Von Willebrand factor (vWf) and increased neutrophil to lymphocyte (N/L) ratio may reflect vascular inflammation in hypertensive patients. In present study, we aimed to investigate the effects of valsartan as an angiotensin II receptor antagonist and amlodipine as a calcium channel blocker on the vWf levels and N/L ratio in(More)
Emergent cardiac surgery during transcatheter aortic valve implantation (TAVI): a weighted meta-analysis of 9,251 patients from 46 studies. Transcatheter aortic valve implantation: first results from a multi-centre real-world registry. Valve Registry (GARY): a nationwide registry for patients undergoing invasive therapy for severe aortic valve stenosis. We(More)
To the Editor: We read with great interest the article 'Usefulness of pre-treatment neutrophil to lymphocyte ratio in predicting disease specific survival in breast cancer patients' by Noh et al. [1]. In the study, they aimed to investigate the prognostic impact of pretreatment neutrophil to lymphocyte (N/L) ratio on breast cancer in view of(More)
OBJECTIVE There is a growing body of data supporting the association between diabetes and microcirculatory disfunction. We aimed to study e-selectin levels, and their associations with serum markers of inflammation and arterial stiffness in prediabetes and newly diagnosed diabetes patients in this study. SUBJECTS AND METHODS Sixty patients (25 females)(More)