Hak-Jong Choi

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The major histocompatibility complex (MHC) class Ib molecule H2-M3 primes the rapid expansion of CD8+ T cells by presenting N-formylated bacterial peptides. However, the significance of H2-M3-restricted T cells in host defense against bacteria is unclear. We generated H2-M3-deficient mice to investigate the role of H2-M3 in immunity against Listeria(More)
Group 1 CD1 (CD1a, CD1b, and CD1c)-restricted T cells recognize mycobacterial lipid antigens and are found at higher frequencies in Mycobacterium tuberculosis (Mtb)-infected individuals. However, their role and dynamics during infection remain unknown because of the lack of a suitable small animal model. We have generated human group 1 CD1 transgenic(More)
Protein functions are often revealed by their localization to specialized cellular sites. Recent reports demonstrated that swiprosin-1 is found together with actin and actin-binding proteins in the cytoskeleton fraction of human mast cells and NK-like cells. However, direct evidence of whether swiprosin-1 regulates actin dynamics is currently lacking. We(More)
A novel, red-pigmented, pleomorphic and short rod-shaped haloarchaeon, designated B8T, was isolated from a salt-fermented seafood. Strain B8T was found to be able to grow at 20–45 °C, in the presence of 15–30 % (w/v) NaCl and at pH 7.0–9.0. The optimum requirements were found to be a temperature range of 35–40 °C, pH 8.0 and the presence of 25 % NaCl. The(More)
Two Gram-stain negative, rod-shaped and motile extreme halophiles, designated CBA1107T and CBA1108, were isolated from non-purified solar salt. Based on the phylogenetic analysis, strains CBA1107T and CBA1108 were shown to belong to the genus Halolamina, with similarities for the 16S rRNA gene sequences between strains CBA1107T and Halolamina pelagica(More)
A halophilic archaeal strain, designated CBA1105T, was isolated from non-purified solar salt. Strain CBA1105T was found to have three 16S rRNA genes, rrnA, rrnB and rrnC; similarities between the 16S rRNA gene sequences were 99.5–99.7 %. The phylogenetic analysis of the 16S rRNA gene sequences showed that strain CBA1105T forms a distinct clade with the(More)
A halophilic archaeon, designed strain CBA1103T, was isolated from non-purified solar salt. The cells of strain CBA1103T were observed to be Gram-stain negative and pleomorphic, and the colonies appear red. Strain CBA1103T was observed to grow between 20 and 55 °C (optimum 37 °C), and in NaCl concentrations of 10–30 % (w/v) (optimum 15 %) with 0–0.5 M(More)
This report describes the draft genome sequence of Lactobacillus plantarum strain wikim18, isolated from the traditional Korean food kimchi. The reads generated by Ion Torrent PGM were assembled into 327 contigs. RAST annotation of the genome revealed 12 tRNAs and 3,316 protein-coding gene sequences.
An extremely halophilic archaeon, Haladaptatus cibarius D43(T), was isolated from traditional Korean salt-rich fermented seafood. Strain D43(T) shows the highest 16S rRNA gene sequence similarity (98.7 %) with Haladaptatus litoreus RO1-28(T), is Gram-negative staining, motile, and extremely halophilic. Despite potential industrial applications of extremely(More)
A Gram-positive, aerobic, non-motile and extremely halophilic bacterial strain, designated K9T, was isolated from kimchi, a Korean fermented food. The strain was observed as endospore-forming rod-shaped cells showing oxidase and catalase activity. It was found to grow at 10.0–30.0 % (w/v) NaCl (optimum, 15.0–20.0 %), pH 7.0–8.0 (optimum, pH 7.5) and 15–40(More)