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DNA microarray profiling studies have led to the classification of invasive breast carcinoma into luminal/estrogen receptor-positive, normal breast-like, Her2/neu-overexpressing, and basal-like types. Among these groups, the basal-like subtype is associated with the poorest clinical outcome in Western countries. To date, the clinicopathologic(More)
OBJECTIVE To evaluate the mammographic and sonographic findings of pregnancy-associated breast cancer. METHODS A total of 22 consecutive patients with breast cancer pathologically diagnosed during pregnancy (n = 10) or lactation (n = 12) were included in this study. The ages of the patients ranged from 26 to 49 years. Both mammography and sonography were(More)
Localized translation of axonal mRNAs contributes to developmental and regenerative axon growth. Although untranslated regions (UTRs) of many different axonal mRNAs appear to drive their localization, there has been no consensus RNA structure responsible for this localization. We recently showed that limited expression of ZBP1 protein restricts axonal(More)
OBJECTIVE The purpose of our study was to retrospectively compare the sonographic and pathologic features of screening-detected and symptomatic ductal carcinoma in situ (DCIS). MATERIALS AND METHODS Of 5,790 cases diagnosed as breast cancer at our institution between January 1998 and December 2005, 528 (9.1%) cases were DCIS. We found 106(More)
OBJECTIVE The objective of our study was to retrospectively assess the potential role of sonographic features and biopsy in the management of patients with papillary lesions diagnosed at percutaneous sonographically guided biopsy. MATERIALS AND METHODS Surgical or sonographic follow-up (> or = 2 years) was available in 123 women (age range, 21-75 years;(More)
Increasing evidence points to the importance of local protein synthesis for axonal growth and responses to axotomy, yet there is little insight into the functions of individual locally synthesized proteins. We recently showed that expression of a reporter mRNA with the axonally localizing β-actin mRNA 3'UTR competes with endogenous β-actin and GAP-43 mRNAs(More)
To evaluate the diagnostic performance of automated breast ultrasound (ABUS) after breast magnetic resonance imaging (MRI) as a replacement for hand-held second-look ultrasound (HH-SLUS), we evaluated 58 consecutive patients with breast cancer who had additional suspicious lesions on breast MRI. All patients underwent HH-SLUS and ABUS. Three breast(More)
OBJECTIVE The purpose of this article is to describe imaging features of the following genitourinary tract locations that can involve inflammatory pseudotumor: kidney, adrenal gland, retroperitoneum or pelvis, bladder, and other rare locations. CONCLUSION Although definite radiologic differentiation from malignancy is not clearly possible, we suggest that(More)
BACKGROUND With the widespread use of PET/CT, incidental hypermetabolic foci unrelated to the known malignancy have been described with increasing frequency. PURPOSE To determine the frequency and clinical significance of incidental focal hypermetabolic uptake in the breast as detected by 18F-FDG PET/CT, and to explore factors differentiating benign and(More)
RATIONALE AND OBJECTIVES To compare the diagnostic accuracy of the Fischer Senoscan Digital Mammography System with that of standard screen-film mammography in a population of women presenting for screening or diagnostic mammography. MATERIALS AND METHODS Enrollment of patients took place at six different breast-imaging centers between 1997 and 1999. A(More)