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  • Toyoshi Inoguchi, Ping-ping Li, +10 authors Hajime Nawata
  • Medicine, Chemistry
  • Diabetes
  • 2000 (First Publication: 1 November 2000)
  • Recent studies have revealed that vascular cells can produce reactive oxygen species (ROS) through NAD(P)H oxidase, which may be involved in vascular injury. However, the pathological role ofExpand
  • Toyoshi Inoguchi, Toshiyo Sonta, +9 authors Hajime Nawata
  • Biology, Medicine
  • Journal of the American Society of Nephrology…
  • 2003 (First Publication: 1 August 2003)
  • Hyperglycemia seems to be an important causative factor in the development of micro- and macrovascular complications in patients with diabetes. Several hypotheses have been proposed to explain theExpand
  • Wuqiang Fan, Toshihiko Yanase, +6 authors Hajime Nawata
  • Biology, Medicine
  • Diabetes
  • 2005 (First Publication: 1 April 2005)
  • Androgen receptor (AR) null male mice (AR(L-/Y)) revealed late-onset obesity, which was confirmed by computed tomography-based body composition analysis. AR(L-/Y) mice were euphagic compared with theExpand
  • Mieko Nakayama, Toyoshi Inoguchi, +8 authors Hajime Nawata
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2005 (First Publication: 1 July 2005)
  • This study was undertaken to reveal the role of NAD(P)H oxidase in increased oxidative stress in islets of Type 2 diabetes. Immunostaining analysis showed that staining intensities of NAD(P)H oxidaseExpand
  • Wuqiang Fan, Toshihiko Yanase, +7 authors Hajime Nawata
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2007 (First Publication: 9 March 2007)
  • The androgen-androgen receptor (AR) system plays vital roles in a wide array of biological processes, including prostate cancer development and progression. Several growth factors, such asExpand